198407-83-9Relevant academic research and scientific papers
A convergent synthesis of the tricyclic core of the dictyosphaeric acids
Barfoot, Christopher W.,Burns, Alan R.,Edwards, Michael G.,Kenworthy, Martin N.,Ahmed, Mahmood,Shanahan, Stephen E.,Taylor, Richard J. K.
, p. 353 - 356 (2008/09/19)
(Chemical Equation Presented) The first synthetic route to the tricyclic core of the dictyosphaeric acids has been established starting from readily available (S)-(-)-4-(tert-butyldimethylsilyloxy)cyclohexenone and involving 9 steps, including a ring-clos
Approaches to the synthesis of (+)- and (-)-epibatidine
Barros, M. Teresa,Maycock, Christopher D.,Ventura, M. Rita
, p. 166 - 173 (2007/10/03)
Synthetic approaches to the powerful analgesic alkaloids (+)- and (-)-epibatidine are described. The starting material employed was natural (-)-quinic acid from which chiral enones and α-iodoenones were prepared. Stille coupling afforded suitable substrat
The effect of DMSO on the borohydride reduction of a cyclohexanone: A formal enantioselective synthesis of (+)-epibatidine
Barros, M. Teresa,Maycock, Christopher D.,Ventura, M. Rita
, p. 557 - 560 (2007/10/03)
An asymmetric synthesis of (+)-epibatidine is described which uses the increased stereoselectivity of a borohydride reduction induced by the presence of DMSO.
First generation of the dienediyne portion of a dienediyne model of the neocarzinostatin chromophore by a McMurry reaction
Rucker, Mark,Brueckner, Reinhard
, p. 7353 - 7356 (2007/10/03)
The first 3→6 type ring-closing dienediyne synthesis by means of a McMurry reaction was realized by converting the ketoaldehyde 20 into the 6-/10-membered bicyclic dienediyne 22. Diastereoselective pinacol couplings 20→23 and 21→24 giving 6-/10-membered b
