198543-08-7

Usage

Uses

Used in Pharmaceutical Industry:
FMOC-ASPARAGINOL(TRT) is used as a key component in the synthesis of peptides for various pharmaceutical applications. Its role in protecting specific functional groups during peptide synthesis allows for the creation of complex peptide sequences with high purity and specificity, which are essential for the development of new drugs and therapeutic agents.
Used in Research and Development:
In the field of research and development, FMOC-ASPARAGINOL(TRT) is employed as a reagent for the synthesis of custom peptides. This enables scientists to explore the properties and functions of these peptides, contributing to advancements in molecular biology, biochemistry, and related disciplines.
Used in Diagnostics:
FMOC-ASPARAGINOL(TRT) is utilized in the development of diagnostic tools, such as peptide-based assays and tests. The ability to synthesize specific peptide sequences with FMOC-ASPARAGINOL(TRT) allows for the creation of targeted diagnostic agents that can detect and measure the presence of certain biomarkers or pathogens.
Used in Biochemical Analysis:
FMOC-ASPARAGINOL(TRT) is used as a tool in biochemical analysis to study the interactions between peptides and other biomolecules. This can provide insights into the mechanisms of various biological processes and help in understanding the structure and function of proteins and peptides.
Overall, FMOC-ASPARAGINOL(TRT) is a versatile compound with applications across various industries, primarily due to its role in peptide synthesis and the ability to protect specific functional groups during the process. Its use in pharmaceuticals, research and development, diagnostics, and biochemical analysis highlights its importance in the field of biotechnology and life sciences.

Upstream product

• 132388-59-1 L-Asn(Trt) 

Downstream Products

• 245523-22-2 N-Triphenylmethyl (3S)-4-(tert-butyldiphenylsilyloxy)-3-(9-fluorenylmethoxycarbonylamino)butyramide 
• 869735-96-6 [1-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-2-(trityl-carbamoyl)-ethyl]-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 245523-40-4 N-Triphenylmethyl (3S)-3-[(2R,3S)-3-azido-4-phenyl-2-triethylsilyloxybutylamino]-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-25-5 N-Triphenylmethyl (3S)-3-[(2S,3S)-3-azido-4-phenyl-2-triethylsilyloxybutylamino]-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-28-8 N-Triphenylmethyl (3S)-3-{N'-[(2S,3S)-3-azido-2-hydroxy-4-phenylbutyl]-N'-[(1R)-1-bromopropylcarbonyl]amino}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-29-9 N-Triphenylmethyl (3S)-3-{N'-[(2S,3S)-3-azido-2-hydroxy-4-phenylbutyl]-N'-[(1R)-1-bromo-2-methylpropylcarbonyl]amino}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-32-4 N-Triphenylmethyl (3S)-3-{(2S,6S)-6-[(1S)-1-azido-2-phenylethyl]-2-isopropylmorpholin-3-one-4-yl}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-41-5 N-Triphenylmethyl (3S)-3-{N'-[(2R,3S)-3-azido-2-hydroxy-4-phenylbutyl]-N'-[(1R)-1-bromoethylcarbonyl]amino}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-27-7 N-Triphenylmethyl (3S)-3-{N'-[(2S,3S)-3-azido-2-hydroxy-4-phenylbutyl]-N'-[(1R)-1-bromoethylcarbonyl]amino}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-30-2 N-Triphenylmethyl (3S)-3-{(2S,6S)-6-[(1S)-1-azido-2-phenylethyl]-2-methylmorpholin-3-one-4-yl}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-42-6 N-Triphenylmethyl (3S)-3-{(2S,6R)-6-[(1S)-1-azido-2-phenylethyl]-2-methylmorpholin-3-one-4-yl}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-39-1 N-Triphenylmethyl (3S)-3-[(2R,3S)-3-azido-2-hydroxy-4-phenylbutylamino]-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-24-4 N-Triphenylmethyl (3S)-3-[(2S,3S)-3-azido-2-hydroxy-4-phenylbutylamino]-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-34-6 N-Triphenylmethyl (3S)-3-{(2S,6S)-6-[(1S)-1-azido-2-phenylethyl]-2-isopropylmorpholin-3-one-4-yl}-4-hydroxybutyramide 

Relevant academic research and scientific papers

A facile synthesis and crystallographic analysis of N-protected β-amino alcohols and short peptaibols

A facile, efficient and racemization-free method for the synthesis of N-protected β-amino alcohols and peptaibols using N-hydroxysuccinimide active esters is described. Using this method, dipeptide, tripeptide and pentapeptide alcohols were isolated in high yields. The conformations in crystals of β-amino alcohol, dipeptide and tripeptide alcohols were analysed, with a well-defined type III β-turn being observed in the tripeptide alcohol crystals. This method is found to be compatible with Fmoc-, Boc- and other side-chain protecting groups.

Synthesis of conformationally restricted mimetics of γ-turns and incorporation into desmopressin, an analogue of the peptide hormone vasopressin

Mimetics of tripeptides adopting inverse and classical γ-turn conformations have been designed and synthesized by an enantioselective approach and then incorporated in an analogue of the hormone vasopressin. In the mimetics one of the amide bonds of the γ