1986-40-9 Usage
Uses
Used in Pharmaceutical Industry:
5-methyl-3-phenyl-2-thioxo-1,3-thiazolidin-4-one is utilized as a therapeutic agent for the treatment of diabetes and obesity due to its potential to modulate metabolic pathways and improve insulin sensitivity.
Used in Anti-inflammatory Applications:
5-methyl-3-phenyl-2-thioxo-1,3-thiazolidin-4-one serves as an anti-inflammatory agent, leveraging its inherent properties to reduce inflammation and alleviate symptoms associated with inflammatory conditions.
Used in Antioxidant Formulations:
5-methyl-3-phenyl-2-thioxo-1,3-thiazolidin-4-one is employed as an antioxidant in various formulations to protect cells from oxidative stress and prevent damage caused by reactive oxygen species.
Used in Antimicrobial Agents:
5-methyl-3-phenyl-2-thioxo-1,3-thiazolidin-4-one is used as an antimicrobial agent, capitalizing on its ability to inhibit the growth of microorganisms, making it a potential candidate for the development of new antibiotics or antifungal agents.
Used in Chemical Research:
5-methyl-3-phenyl-2-thioxo-1,3-thiazolidin-4-one is utilized as a subject of study in chemical research to explore its structure-activity relationships and to uncover new applications in various fields, including material science and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1986-40-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,8 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1986-40:
(6*1)+(5*9)+(4*8)+(3*6)+(2*4)+(1*0)=109
109 % 10 = 9
So 1986-40-9 is a valid CAS Registry Number.
1986-40-9Relevant academic research and scientific papers
A New Synthesis Strategy for Rhodanine and Its Derivatives
Pan, Zhenliang,An, Wankai,Wu, Lulu,Fan, Liangxin,Yang, Guoyu,Xu, Cuilian
, p. 1131 - 1134 (2021/05/25)
Rhodanine and its derivatives have been known as privileged structures in pharmacological research because of their wide spectrum of biological activities, but the synthesis method of rhodanine skeleton is limited. In this paper, not only rhodanine skeleton, but also N -aryl rhodanines can be directly prepared via the reaction of thioureas and thioglycolic acid in one step catalyzed by protic acid, which provides a new approach of the synthesis of rhodanine and its derivatives. The developed strategy is straightforward, efficient, atom economical, and convenient in good yields.
Asymmetric michael addition of substituted rhodanines to α,β-unsaturated ketones catalyzed by bulky primary amines
Yu, Feng,Hu, Haoxiang,Gu, Xiaodong,Ye, Jinxing
supporting information; experimental part, p. 2038 - 2041 (2012/07/28)
A bulky group was introduced by design into a diamine catalyst, and a series of robust and tunable bulky chiral primary amine catalysts were developed and successfully applied in the direct conjugate addition of substituted rhodanines to α,β-unsaturated ketones. High yields (up to 99%) and excellent diastereoselectivities (up to 99:1 dr) and enantioselectivities (up to 98% ee) were observed.
