198635-41-5Relevant academic research and scientific papers
Stereoselective synthesis of β-amino alcohols: Diastereoselective reduction of chiral α-amino enones derived from amino acids
Chung, Sung-Kee,Kang, Dong-Ho
, p. 3027 - 3030 (2007/10/03)
α-Amino acids are doubly benzylated at nitrogen to give N,N-dibenzyl amino acids, which can readily be converted to α'-amino enones 3. The α'-amino enones are very resistant to racemization, and undergo highly diastereoselective reduction to afford chiral amino alcohols upon treatment with L-Selectride under non-chelation control.
