198641-81-5Relevant academic research and scientific papers
Cross β-arylmethylation of alcohols catalysed by recyclable Ti-Pd alloys not requiring pre-activation
Utsunomiya, Masayoshi,Kondo, Ryota,Oshima, Toshinori,Safumi, Masatoshi,Suzuki, Takeyuki,Obora, Yasushi
supporting information, p. 5139 - 5142 (2021/05/31)
Ti-Pd alloy catalysts were developed for the cross β-arylmethylation between arylmethylalcohols and different primary alcohols via a hydrogen autotransfer mechanism. The alloy catalysts could be reused multiple times without the need for pre-activation. Analysis of the reaction solution by inductively coupled plasma atomic absorption spectroscopy indicated that only a minimal amount of Ti and no Pd was leached from the catalyst.
First practical cross-alkylation of primary alcohols with a new and recyclable impregnated iridium on magnetite catalyst
Cano, Rafael,Yus, Miguel,Ramon, Diego J.
supporting information; experimental part, p. 7628 - 7630 (2012/09/25)
A new impregnated iridium on magnetite catalyst has been prepared, characterized, used and recycled, up to ten times with practically the same activity, for the first practical cross-alkylation of primary alcohols. The catalyst showed a wide reaction scope, is easy to prepare and handle, and it could be removed from the reaction medium just by magnetic sequestering.
Design and synthesis of novel 2,7-dialkyl substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides as in vitro potent peptidomimetic inhibitors of human renin
Goeschke, Richard,Cohen, Nissim Claude,Wood, Jeanette M.,Maibaum, Juergen
, p. 2735 - 2740 (2007/10/03)
Novel low-molecular weight transition-state peptidomimetic renin inhibitors characterized by an all-carbon 8-phenyl substituted octanecarboxamide skeleton have been discovered based on a topographical design approach. The in vitro most potent inhibitors 21, 25 and 26 incorporating a strong H-bond acceptor group linked to the benzyl spacer of the (P3-P1)-unit had IC50s in the low nanomolar range against human renin.
