198642-64-7

Basic information

• Product Name: (R)-N-Benzyl-N-((R)-2-hydroxy-1-phenyl-ethyl)-3-phenyl-succinamic acid tert-butyl ester
• Synonyms: (R)-N-Benzyl-N-((R)-2-hydroxy-1-phenyl-ethyl)-3-phenyl-succinamic acid tert-butyl ester
• CAS NO: 198642-64-7
• Molecular Weight: 459.585
• Mol File: 198642-64-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-N-Benzyl-N-((R)-2-hydroxy-1-phenyl-ethyl)-3-phenyl-succinamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-Benzyl-N-((R)-2-hydroxy-1-phenyl-ethyl)-3-phenyl-succinamic acid tert-butyl ester(198642-64-7)
• EPA Substance Registry System: (R)-N-Benzyl-N-((R)-2-hydroxy-1-phenyl-ethyl)-3-phenyl-succinamic acid tert-butyl ester(198642-64-7)

Safety Data

• Hazardous Substances Data: 198642-64-7(Hazardous Substances Data)

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 

Downstream Products

• 1078-21-3 (R)-Phenibut 
• 198642-70-5 (R)-4-[Benzyl-((R)-2-hydroxy-1-phenyl-ethyl)-amino]-3-phenyl-butyric acid tert-butyl ester 

Relevant articles and documents

Enantioselective synthesis of β-substituted primary and secondary amines by alkylation of (R)-phenylglycinol amide enolates

General and convenient syntheses of optically active β-substituted secondary or primary amines 4 and 8 are described. The method is based on diastereoselective alkylation of amides 1 and 5 derived from R-(-)-phenylglycinol followed by reduction and removal of the chiral appendage. This procedure has also been applied to the preparation of 1,4-amino alcohols 12 and γ-amino esters 14.