19865-62-4

Usage

Uses

Used in Pharmaceutical Industry:
(4-Chlorophenyl)(2-methoxybenzylidene)azane oxide is used as a potential therapeutic agent for its potential anticonvulsant and anti-inflammatory properties. Its application in this industry is due to its biological activities that may help in the treatment of various conditions related to seizures and inflammation.
Used in Organic Synthesis:
(4-Chlorophenyl)(2-methoxybenzylidene)azane oxide is used as a reagent in organic synthesis for its ability to contribute to the formation of complex molecular structures. Its application in this industry is due to its chemical properties that facilitate the synthesis of other compounds with potential applications in various fields.

Upstream product

• 135-02-4 ortho-anisaldehyde 
• 823-86-9 N-(4-chlorophenyl)hydroxylamine 
• 100-00-5 4-chlorobenzonitrile 

Relevant academic research and scientific papers

Synthesis and Evaluation of Novel 5-cyclohexyl-2-(4″-substitutedphenyl)-3-(2″-substitutedphenyl)4H-2,3,3a,5,6,6a-hexahydropyrrolo[3,4-d]isoxazole-4,6-dione Derivatives for Their In Vitro Antioxidant and Antibacterial Activities

1,3-Dipolar cycloaddition reactions of N-cyclohexyl maleimide (1) with azomethine N-oxide (2) have afforded novel isoxazolidine (3) in excellent yield. Their structures have been characterized from their IR,1H-NMR,13C-NMR,1H,1H-COSY, MS(ESI), and elemental analysis techniques. In vitro antibacterial activity of the synthesized compounds were investigated against a representative panel of pathogenic strains specifically two Gram-positive bacteria (Staphylococcus aureus and Streptococcus pyogenes) and two Gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli) using agar-well diffusion assay. Some of the compounds (3a, 3k, 3n, and 3o) exhibited promising antibacterial activities. All the synthesized compounds have also been screened for their antioxidant activities and were found to be significantly active.