1987-50-4

Usage

Uses

Used in Environmental Studies:
4-N-Heptylphenol is used as a marker for environmental pollution in the field of environmental studies. Its presence has been detected in the eggs of three seabird species from remote colonies in Norway, indicating its widespread distribution as an environmental pollutant.
Used in Endocrine Disruption Research:
4-N-Heptylphenol is used as a research compound for studying the effects of endocrine disruption in animals. Its estrogenic activity allows scientists to investigate the potential impacts of 4-N-HEPTYLPHENOL on the hormonal balance and reproductive health of various species.
Used in Chemical Synthesis:
As a clear brown liquid after melting, 4-N-Heptylphenol may also be used as a starting material or intermediate in the synthesis of various chemical products, particularly those related to the pharmaceutical or agrochemical industries. Its unique chemical properties make it a valuable component in the development of new compounds with specific applications.

InChI:InChI=1S/C13H20O/c1-2-3-4-5-6-7-12-8-10-13(14)11-9-12/h8-11,14H,2-7H2,1H3

Upstream product

• 111-71-7 heptanal 
• 108-95-2 phenol 
• 106-41-2 4-bromo-phenol 
• 13125-66-1 n-heptylmagnesium bromide 
• 106379-86-6 1-(4-hydroxy-phenyl)-heptan-1-ol 
• 2528-61-2 Heptanoic acid chloride 
• 111-25-1 1-bromo-hexane 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 14392-72-4 4-heptanoylphenol 
• 92368-72-4 1-heptyl-4-methoxybenzene 
• 56052-14-3 heptanoic acid phenyl ester 

Downstream Products

• 18980-06-8 2-chloro-4-heptylphenol 
• 81259-72-5 2-nitro-4-heptylphenol 
• 109507-15-5 dichlorophosphoric acid-(4-heptyl-phenyl ester) 
• 4097-32-9 4-heptyl-2,6-dinitro-phenol 
• 38444-22-3 4'-heptylphenyl-4-butylbenzoate 
• 38444-23-4 4-Hexyl-benzoic acid 4-heptyl-phenyl ester 
• 38444-25-6 4-Butoxy-benzoic acid 4-heptyl-phenyl ester 
• 38444-26-7 4-Hexyloxy-benzoic acid 4-heptyl-phenyl ester 
• 16618-75-0 4-n-heptylcyclohexanone 
• 108769-91-1 4-Heptyl-1-(4-trifluoromethyl-phenyl)-cyclohexanol 
• 108769-94-4 4-Heptyl-1-(4-trifluoromethyl-phenyl)-cyclohexanol 
• 1266554-70-4 N,N'-hexanediyldicarbamic acid di(4-(1,1,3,3-tetramethylbutyl)phenyl) ester 
• 146519-46-2 3-(4-n-heptylphenoxy)-propane-1,2-diol 
• 1448537-47-0 1-(allyloxy)-4-n-heptylbenzene 

Relevant academic research and scientific papers

Iron-catalyzed reductive dehydroxylation of benzylic alcohols using polymethylhydrosiloxane (PMHS)

The combination of FeCl3 and PMHS is an efficient reducing system for the selective dehydroxylation of secondary benzylic alcohols, even in the presence of carbonyls, under very mild conditions. Georg Thieme Verlag Stuttgart · New York.

Scope and limitations of lithium-ethylenediamine-THF-mediated cleavage at the α-position of aromatics: Deprotection of aryl methyl ethers and benzyl ethers under mild conditions

The scope and limitation of lithium-ethylenediamine-THF-mediated reductive bond cleavage at the α-position of aromatics were examined. Very mild conditions such as lithium metal (5 equiv) and ethylenediamine (7 equiv) in oxygen-free THF were quite effective for the demethylation of aromatic ethers even at as low as -10°C. Allyl benzyl ethers were also deprotected under these conditions with very little change of the allylic alcohol moiety. Through this study, 2,6-dimethylbenzyl (m-xylylmethyl, MXM) group was developed as an alternative of benzyl group, which is readily cleavable under the above mentioned reductive conditions.

Palladium catalyzed cross-coupling reaction of Grignard reagents with halobenzoic acids, halophenols and haloanilines

Convenient syntheses of substituted benzoic acids, phenols and anilines have been achieved by using palladium catalyzed cross-coupling reactions between Grignard reagents and aryl halides containing carboxy, hydroxy and amino groups without a protection-deprotection sequence.

Metal cation-exchanged montmorillonite (Mn+-mont)-catalysed aromatic alkylation with aldehydes and ketones

The alkylation of aromatic compounds with aldehydes and ketones in the presence of a variety of metal cation-exchanged montmorillonites (Mn+-mont; Mn+ = Zr4+, Al3+, Fe3+, Zn2+, H+, Na+) has been investigated. Al3+- and Zr4+-Monts are revealed to be effective as catalysts, while no reaction takes place with Na+-mont. Al3+-Mont-catalysed alkylation of phenol with several aldehydes produces mainly or almost solely the corresponding gem-bis(hydroxyphenyl)alkanes (bisphenols) in good yields, while that with several ketones affords selectively the corresponding alkylphenols in moderate to good yields. The alkylation always occurs at the carbonyl carbon without any skeletal rearrangement and the kind of products depends much on the steric hindrance of an electrophilic intermediary carbocation. The alkylation of anisole, veratrole and p-cresol proceeds well, while that of toluene, benzene, chlorobenzene and nitrobenzene scarcely occurs.

Preparation of diphenolics

A process for the production of diphenolic compounds having a divalent bridge. A first disubstituted phenol is reacted with an aldehyde in the presence of a secondary amine and excess alcohol to form an ether intermediate. The ether intermediate is reacted with a phenol having an open ortho or para position to form a diphenolic.

RECHERCHES SUR LES SUBSTANCES MESOGENES-VIII; PREPARATION ET PROPERTIES MESOMORPHES DE SERIES ISOMETRIQUES

The synthesis and the mesomorphic properties of various series of isometric mesogenic compounds are described.It is confirmed that isometric mesogenic molecules may be nematogenic and/or smectogenic according to the position of the polar rigid core.