198707-57-2

Basic information

• Product Name: (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOIC ACID
• Synonyms: BUTTPARK 88\04-21;AKOS BAR-2485;(2E)-3-(2,3-DIHYDRO-1-BENZOFURAN-5-YL)ACRYLIC ACID;(2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOIC ACID;3-(2,3-DIHYDRO-BENZOFURAN-5-YL)-ACRYLIC ACID;3-(2,3-DIHYDRO-BENZOFURAN-5-YL)PROPENOIC ACID;3-(2,3-DIHYDRO-1-BENZOFURAN-5-YL)ACRYLIC ACID;RARECHEM BK HW 0114
• CAS NO: 198707-57-2
• Molecular Formula: C11H10O3
• Molecular Weight: 190.2
• Mol File: 198707-57-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 170-173°C
• Appearance: /
• CAS DataBase Reference: (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOIC ACID(198707-57-2)
• EPA Substance Registry System: (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOIC ACID(198707-57-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 198707-57-2(Hazardous Substances Data)

Usage

General Description

"(2E)-3-(2,3-Dihydrobenzofuran-5-yl)propenoic acid" is a chemical compound that consists of a propenoic acid functional group and a benzofuran ring. It is classified as an unsaturated carboxylic acid due to the presence of the propenoic acid group, and it contains a benzofuran ring, which makes it part of the furan group of chemicals. (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOIC ACID has potential applications in organic synthesis and medicinal chemistry due to its unique structure, which may impart specific biological or chemical properties. Further research and investigation are needed to fully understand the chemical and biological properties of this compound and its potential applications.

Upstream product

• 496-16-2 2.3-dihydrobenzofuran 
• 55745-70-5 2,3-dihydro-benzofuran-5-carbaldehyde 
• 141-82-2 malonic acid 

Downstream Products

• 215057-28-6 3-(2,3-dihydro-1-benzofuran-5-yl)propanoic acid 
• 1412271-07-8 C₂₃H₂₃N₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412271-47-6 C₂₄H₂₅N₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412271-59-0 C₂₄H₂₄BrN₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412271-83-0 C₂₆H₂₃N₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412271-87-4 C₂₇H₂₅N₂O₃⁽¹⁺⁾*Br^(1-) 
• 1412271-99-8 C₂₆H₂₂BrN₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412270-66-6 C₂₂H₂₁N₂O₂⁽¹⁺⁾*Br^(1-) 

Relevant articles and documents

Dihydrofuran and yinyin alkane - imidazole salt compound and its preparation method

The invention discloses a series of dihydrofuran indenoane-imidazole salts compounds and a preparation method thereof. The preparation method comprises the following steps of: carrying out Vilsmeier reaction and Perskin reaction on 2,3-dihydrobenzofuran taken as a raw material; reducing palladium/carbon in an acetic acid to 5-propionic acid dihydrobenzofuran and forming acyl chloride with thionyl chloride; carrying out intramolecular Friedel-Crafts reaction and reducing in an alcohol solution by using sodium borohydride to obtain dihydrofuran indenoanol; forming a chloride in a toluene solution with the thionyl chloride; and reflowing and reacting with imidazole or 2-methyl imidazole or 2-ethyl imidazole or benzimidazole in acetonitrile or a toluene solvent to synthesize 1-(dihydrofuran indenoane) imidazole, and reacting with a halide on the above basis to synthesize the compound. According to the dihydrofuran indenoane-imidazole salts compounds and the preparation method thereof, pharmacophores with obvious tumor resisting activity in natural products are used as precursors to carry out designing and synthesizing on anti-tumor medicine molecule, and when an imidazole structure unit in a synthesized compound is the benzimidazole, particularly a naphthoyl methyl imidazole salts compound, the compound has very good in-vitro anticancer physiological activity.

PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES

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