496-16-2Relevant articles and documents
Stereoselective cyclizations mediated by functionalized organomagnesium reagents and catalyzed by cobalt or copper salts
Kneisel, Florian F.,Monguchi, Yasunari,Knapp, Kolja M.,Zipse, Hendrik,Knochel, Paul
, p. 4875 - 4879 (2002)
The iodine-magnesium exchange reaction with i-PrMgCl allows a mild preparation of functionalized arylmagnesium compounds bearing a leaving group in the molecule. With the appropriate transition-metal catalyst (a copper or cobalt salt), cyclization reactions occur leading to five- or six-membered ring systems in good yields.
A novel catalyst Pd@ompg-C3N4 for highly chemoselective hydrogenation of quinoline under mild conditions
Gong, Yutong,Zhang, Pengfei,Xu, Xuan,Li, Yi,Li, Haoran,Wang, Yong
, p. 272 - 280 (2013)
Polymeric mesoporous carbon graphitic nitrides (mpg-C3N 4) and ordered mesoporous graphitic carbon nitrides (ompg-C 3N4) with different surface area and morphology were used to prepare palladium catalysts (Pd@C3N4) by an easy ultrasonic-assisted method. These catalysts demonstrated excellent activity and selectivity for hydrogenation of quinoline to 1,2,3,4-tetrahydroquinoline under mild temperature (30-50 °C) and H2 pressure (1 bar). Pd@ompg-C3N4(r = 2.5) showed the best catalytic performance and both the activity and selectivity could be maintained for at least six reaction runs. The introduction of ordered cylindrical mesoporous structure and high concentration of surface Pd0 (about 70%) contribute to the high reaction activity and selectivity over Pd@ompg-C 3N4 catalysts.
Heterogeneous Hydrogenation of Quinoline Derivatives Effected by a Granular Cobalt Catalyst
Timelthaler, Daniel,Topf, Christoph
, (2021/11/22)
We communicate a convenient method for the pressure hydrogenation of quinolines in aqueous solution by using a particulate cobalt-based catalyst that is prepared in situ from simple Co(OAc)2 4H2O through reduction with abundant zinc powder. This catalytic protocol permits a brisk and atom-efficient access to a variety of 1,2,3,4-tetrahydroquinolines thereby relying solely on easy-to-handle reagents that are all readily obtained from commercial sources. Both the reaction setup assembly and the autoclave charging procedure are conducted on the bench outside an inert-gas-operated containment system, thus rendering the overall synthesis time-saving and operationally very simple.
Preparation of NiCu Alloy Catalyst for the Hydrodeoxygenation of Benzofuran
Zhu, Tianhan,Song, Hua,Li, Feng,Chen, Yanguang
, p. 1670 - 1682 (2020/10/21)
A series of bimetallic NixCu(10-x)/SiO2 (where x is the mass fraction of Ni and the total metal loading was fixed at 10 wt%.) catalysts with different Ni/Cu mass ratio are prepared and characterized by X-Ray diffraction (XRD), N2 adsorption-desorption, inductively coupled plasma mass spectrometry (ICP-MS), H2 temperature-programmed reduction (H2-TPR) and transmission electron microscope (TEM). The benzofuran (BF) hydrodeoxygenation (HDO) performance of as-prepared catalysts are evaluated in a fixed flow reactor. The results showed that the incorporation of Cu to Ni/SiO2 catalyst can increase surface area of catalyst and improve the reducibility of nickel oxide species, which contributed to higher catalytic activity and total deoxygenated compounds yield. Moreover, the strong synergistic effect between Ni and Cu led to the formation of NiCu alloy at the Ni mass fraction of 5 wt% and thus induced smaller crystallite size and exposure of more active particles, which inevitably contributed to the improved HDO performance for Ni5Cu5/SiO2 catalyst. At 300 °C, 3.0 MPa, MHSV=3.0 h?1 and H2/oil = 500(v/v), the total yield of deoxygenated products over Ni5Cu5/SiO2 catalyst reached 86.0%, which is increased by 10.8% and 77.4% as compared to those of monometallic Ni/SiO2 (75.2%) and Cu/SiO2 catalysts (8.8%), respectively. Finally, a possible reaction network for HDO of BF on Ni5Cu5/SiO2 catalyst was proposed. Graphic Abstract: [Figure not available: see fulltext.]
