198823-20-0

Basic information

• Product Name: 3-[3-(1-benzyl-piperidin-4-yl)-2-oxo-imidazolidin-1-yl]-benzonitrile
• CAS NO: 198823-20-0
• Molecular Weight: 360.459
• Mol File: 198823-20-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[3-(1-benzyl-piperidin-4-yl)-2-oxo-imidazolidin-1-yl]-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[3-(1-benzyl-piperidin-4-yl)-2-oxo-imidazolidin-1-yl]-benzonitrile(198823-20-0)
• EPA Substance Registry System: 3-[3-(1-benzyl-piperidin-4-yl)-2-oxo-imidazolidin-1-yl]-benzonitrile(198823-20-0)

Safety Data

• Hazardous Substances Data: 198823-20-0(Hazardous Substances Data)

Upstream product

• 198823-19-7 N-(3-cyanophenyl)-N'-(2-hydroxyethyl)-N'-(1-benzylpiperidin-4-yl)urea 
• 130818-96-1 2-((1-benzylpiperidin-4-yl)amino)ethanol 
• 50541-93-0 4-amino-1-benzylpiperidine 

Relevant articles and documents

The de novo design and synthesis of cyclic urea inhibitors of factor Xa: Initial sar studies

In this report we discuss the design, synthesis, and validation of a novel series of cyclic urea inhibitors of the blood coagulation protein Factor Xa. This work culminates in compound 11, a monoamidine inhibitor of fXa employing a new S4 ligand that reduces the cationic character of these analogs. Compound 11 represents a lead for a series of more potent and selective inhibitors.