198963-19-8

Basic information

• Product Name: 1-[(R)-3,10-Bis-(tert-butyl-dimethyl-silanyloxy)-dec-6-ynyloxymethyl]-4-methoxy-benzene
• Synonyms: 1-[(R)-3,10-Bis-(tert-butyl-dimethyl-silanyloxy)-dec-6-ynyloxymethyl]-4-methoxy-benzene
• CAS NO: 198963-19-8
• Molecular Weight: 534.927
• Mol File: 198963-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(R)-3,10-Bis-(tert-butyl-dimethyl-silanyloxy)-dec-6-ynyloxymethyl]-4-methoxy-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(R)-3,10-Bis-(tert-butyl-dimethyl-silanyloxy)-dec-6-ynyloxymethyl]-4-methoxy-benzene(198963-19-8)
• EPA Substance Registry System: 1-[(R)-3,10-Bis-(tert-butyl-dimethyl-silanyloxy)-dec-6-ynyloxymethyl]-4-methoxy-benzene(198963-19-8)

Safety Data

• Hazardous Substances Data: 198963-19-8(Hazardous Substances Data)

Upstream product

• 198963-26-7 (S)-1-Iodo-5-(4-methoxy-benzyloxy)-pentan-3-ol 
• 198963-17-6 (R)-5-(4-Methoxy-benzyloxy)-pentane-1,3-diol 
• 736140-63-9 5-(4-methoxy)benzyloxy-2R,3S-epoxy-1-pentanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 5390-04-5 pent-1-yn-5-ol 
• 61362-77-4 5-[tert-butyldimethylsilyloxy]pent-1-yne 
• 198963-18-7 tert-Butyl-[(S)-1-(2-iodo-ethyl)-3-(4-methoxy-benzyloxy)-propoxy]-dimethyl-silane 

Downstream Products

• 198963-24-5 (2S,13R)-5-Benzenesulfonyl-1-benzyloxy-2,13-bis-(tert-butyl-dimethyl-silanyloxy)-15-(4-methoxy-benzyloxy)-pentadec-9-yn-6-ol 
• 198963-16-5 (3R,14S)-15-Benzyloxy-3,14-bis-(tert-butyl-dimethyl-silanyloxy)-1-(4-methoxy-benzyloxy)-pentadecane-6,7,10-trione 
• 198963-25-6 (2S,13R)-1-Benzyloxy-2,13-bis-(tert-butyl-dimethyl-silanyloxy)-15-(4-methoxy-benzyloxy)-pentadec-9-yn-6-one 
• 198963-15-4 (2R,6S,8S,10S)-10-Benzyloxymethyl-2-[2-(4-methoxy-benzyloxy)-ethyl]-1,7,9-trioxa-dispiro[5.1.5.2]pentadecan-5-one 
• 198963-14-3 (2R,5S,6S,8S,10S)-10-Benzyloxymethyl-2-[2-(4-methoxy-benzyloxy)-ethyl]-5-methyl-1,7,9-trioxa-dispiro[5.1.5.2]pentadecan-5-ol 
• 198963-21-2 (R)-8-(tert-Butyl-dimethyl-silanyloxy)-10-(4-methoxy-benzyloxy)-dec-4-ynal 
• 198963-20-1 (R)-8-(tert-Butyl-dimethyl-silanyloxy)-10-(4-methoxy-benzyloxy)-dec-4-yn-1-ol 

Relevant articles and documents

The first construction of the B,C,D-ring fragment of pinnatoxins via highly stereocontrolled acetallization

The synthesis of the B,C,D-ring fragment of pinnatoxins is described. The highly stereocontrolled construction of the 6,5,6-tris-spiroacetal core was achieved on treatment of compound 3 with aqueous HF in CH3CN. The anomeric effect at C16 enhanced by neighboring carbonyl group led to form the tris-spiroacetal having the natural configuration.