19909-11-6

Basic information

• Product Name: 1-(4-cyclopentylphenyl)-2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanol
• Synonyms: 1-(4-cyclopentylphenyl)-2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanol
• CAS NO: 19909-11-6
• Molecular Formula: C₁₉H₃₀N₂O₂
• Molecular Weight: 318.4537
• Mol File: 19909-11-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-cyclopentylphenyl)-2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-cyclopentylphenyl)-2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanol(19909-11-6)
• EPA Substance Registry System: 1-(4-cyclopentylphenyl)-2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanol(19909-11-6)

Safety Data

• Hazardous Substances Data: 19909-11-6(Hazardous Substances Data)

Usage

General Description

1-(4-cyclopentylphenyl)-2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanol, also known as pizotifen, is a pharmaceutical compound with antihistamine and serotonin antagonist properties. It is commonly used to prevent migraines and cluster headaches by blocking the action of serotonin in the brain. Pizotifen is thought to reduce the frequency and severity of migraines by preventing the release of certain chemicals in the brain that can cause the blood vessels to widen and the nerves to become overexcited. It is typically taken orally and has a long duration of action, making it particularly useful for chronic migraine management. Pizotifen is considered to be a well-tolerated and effective treatment for preventing migraines and is available by prescription in many countries.

Upstream product

• 85689-78-7 α-bromo-4-(1-cyclopentyl)acetophenone 
• 85689-77-6 1-(4-cyclopentylphenyl)ethan-1-one 
• 103-76-4 1-(2-hydroxyethyl)piperazine 
• 19909-07-0 1-(4-cyclopentyl-phenyl)-2-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-ethanone 

Relevant articles and documents

N-substituted aminomethyl 4-cyclopentylphenyl ketones and 2-amino-1-(4-cyclopentylphenyl)ethanols; synthesis and pharmacological screening

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