199175-10-5

Basic information

• Product Name: (S)-1-Boc-3-(aminomethyl)pyrrolidine
• Synonyms: (S)-1-BOC-3-AMINOMETHYLPYRROLIDINE;(S)-1-N-BOC-3-(AMINOMETHYL)PYRROLIDINE;(S)-3-(AMINOMETHYL)-1-N-BOC-PYRROLIDINE;(S)-3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(S)-TERT-BUTYL-3-(AMINOMETHYL)PYRROLIDINE-1-CARBOXYLATE;3(S)-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(S)-N-BOC-3-(AMINOMETHYL)PYRROLIDINE;(S)-1-tert-Butoxycarbonyl-3-(aminomethyl)pyrrolidine
• CAS NO: 199175-10-5
• Molecular Formula: C₁₀H₂₀N₂O₂
• Molecular Weight: 200.28
• Product Categories: pharmacetical;Pyrrole&Pyrrolidine&Pyrroline;Heterocycle-other series
• Mol File: 199175-10-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 280.3 °C at 760 mmHg
• Flash Point: 123.3 °C
• Appearance: Colorless to yellow/Liquid
• Density: 1.044 g/cm³
• Vapor Pressure: 0.0038mmHg at 25°C
• Refractive Index: 1.4780
• Storage Temp.: 2-8°C
• PKA: 10.12±0.29(Predicted)
• Sensitive: Air Sensitive
• CAS DataBase Reference: (S)-1-Boc-3-(aminomethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Boc-3-(aminomethyl)pyrrolidine(199175-10-5)
• EPA Substance Registry System: (S)-1-Boc-3-(aminomethyl)pyrrolidine(199175-10-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• TSCA: No
• Hazardous Substances Data: 199175-10-5(Hazardous Substances Data)

Usage

General Description

(S)-1-Boc-3-(aminomethyl)pyrrolidine is a chemical compound primarily utilized in scientific research and the pharmaceutical industry. This white solid compound falls under the category of protected amino acids and peptides due to its Boc (tert-butoxycarbonyl) group, which is used to protect the amine group during chemical synthesis. It is often used as a reagent or building block in the synthesis of more complex chemical compounds. Since it is a chiral compound, it can also be used in the creation of various drugs or medications that require a specific orientation of atoms. As a potent chemical, it must always be handled with caution to minimize potential risks or reactions.

InChI:InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)12-5-4-8(6-11)7-12/h8H,4-7,11H2,1-3H3/t8-/m0/s1

Upstream product

• 132945-75-6 (S)-tert-butyl 3-(methylsulfonyloxy)pyrrolidine-1-carboxylate 
• 132945-76-7 tert-butyl (3R)-3-cyano-1-pyrrolidinecarboxylate 
• 101469-92-5 (S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 10442-39-4 tetra-n-butylammonium cyanide 

Downstream Products

• 872714-75-5 tert-butyl (S)-3-(N-benzyloxycarbonyl)aminomethylpyrrolidine-1-carboxylate 
• 1152088-72-6 (S)-tert-butyl 3-((4-(3-iodobenzylamino)-5-nitropyrimidin-2-ylamino)methyl)pyrrolidine-1-carboxylate 
• 1152088-41-9 (S)-tert-butyl 3-((4-(2,3-dichlorobenzylamino)-5-nitropyridin-2-ylamino)methyl)pyrrolidine-1-carboxylate 
• 1152088-82-8 (S)-tert-butyl 3-((4-(3-iodo-2-methylbenzylamino)-5-nitropyrimidin-2-ylamino)methyl)pyrrolidine-1-carboxylate 
• 1152088-92-0 (S)-tert-butyl 3-((4-((R)-1-(2,5-dichlorophenyl)ethylamino)-5-nitropyrimidin-2-ylamino)methyl)pyrrolidine-1-carboxylate 
• 1366767-71-6 1,1-dimethylethyl (3S)-3-({[(4-bromophenyl)carbonyl]amino}methyl)-1-pyrrolidinecarboxylate 
• 1366767-72-7 1,1-dimethylethyl (3R)-3-{[5-(4-bromophenyl)-1H-tetrazol-1-yl]methyl}-1-pyrrolidinecarboxylate 
• 1366767-74-9 5-(4-bromophenyl)-1-{[(3R)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl}-1H-tetrazole 

Relevant articles and documents

Novel pyrrolidine or piperidine derivatives having activity for T-type calcium channel

A pyrrolidine or piperidine compound having activity for T - type calcium channel, wherein the pyrrolidine or piperidine compound of Formula 1 according to the present invention has an excellent antagonistic activity to, T-type calcium channel, and can be used as a preventive or therapeutic agent, for pain diseases, or cancer related to cancer, or cancer such as, epilepsy and,hepatic pain, angina. (by machine translation)

FATTY ACID SYNTHASE INHIBITORS

This invention relates to the use of imidazole, triazole, and tetrazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of imidazoles, triazoles, and tetrazoles in the treatment of cancer.

AZABENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS

This invention relates to the use of azabenzimidazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of azabenzimidazoles in the treatment of cancer.