19925-84-9

Upstream product

• 91-56-5 indole-2,3-dione 
• 95-55-6 2-amino-phenol 

Relevant academic research and scientific papers

Synthesis, spectral investigation of Ni(II) schiff base complexes: Antimicrobial activities and catalytic oxidation of alcohols

Air stable Ni(II) Schiff base complexes viz. [Ni(L1)(PPh3)] and [Ni(L2)(PPh3)] [where L1 and L2 are dianions of Schiff base ligands, respectively] have been synthesized and characterized by analytical and spectral (electronic, FT-IR, 1H, 13C and 31P NMR) methods. The assignment of all the aromatic carbon-hydrogen resonances is made on the basis of 1H-13C HSQC spectrum of the complexes. The Schiff base ligands behave as a bibasic tridentate ligands and bonded through ONO and ONS mode. A square planar structure has been proposed on the basis of spectral data. Novel Ni(II) Schiff base complexes exhibited good antimicrobial activity towards the strains Staphylococcus epidermidis and Escherichia coli. Thermal and air stability of the complexes offer the advantage of oxidation of alcohols.

Lambert Salt-Initiated Development of Friedel–Crafts Reaction on Isatin to Access Distinct Derivatives of Oxindoles

Herein, a mild metal-free and efficacious route for the synthesis of biologically important 3-aryl oxindole derivatives is described. Using Lambert salt-initiated hydroarylation of isatin, a diverse array of monoarylated products, symmetrical/unsymmetrical double-arylated products, and deoxygenated hydroarylated products could be synthesized from the single starting substrate in good to excellent yields. A preliminary mechanistic study revealed that the reaction proceeds via a monoarylated product followed by a nucleophilic attack by another electron-rich arene nucleophile under mild conditions. The potential of newly synthesized symmetric/unsymmetric 3,3-disubstituted oxindole, 3-substituted 3-hydroxy oxindoles, 3,3-di(indolyl)indolin-2-ones, and α-aryl oxindoles as valuable building blocks is further illustrated.

A greener, facile and scalable synthesis of indole derivatives in water: Reactions of indole-2,3-diones with 1,2-difunctionalized benzene

An efficient, facile and greener protocol for the synthesis of indole derivatives viz., 3'H-spiro[indole- 3,2'-[1,3]benzothiazole]-2(1H)-ones, 6H-indolo[2,3-b]quinoxalines and 3-(2-hydroxy-phenylimino)- 1,3-dihydro-indol-2- ones, by the reactions of indol

Biocidal and catalytic efficiency of ruthenium(III) complexes with tridentate Schiff base ligands

The reaction of the Schiff bases (obtained by condensing isatin with o-aminophenol/o-aminothiophenol/o-aminobenzoic acid) with [RuX 3(EPh3)3] (where X = Cl/Br; E = P/As) in benzene afforded new, air-stable Ru(III) complexes of the general formula [Ru(L)X(EPh3)2] (L = dianion of tridentate Schiff bases). In all these reactions, the Schiff base ligand replaces one triphenylphosphine/ triphenylarsine and two chlorides/bromides from the ruthenium precursors. The complexes were characterized by elemental analyses, spectral (FT-IR, UV-vis,1H and 13C NMR for the ligands, and EPR) and electrochemical studies. All the metal complexes exhibit characteristic LMCT absorption bands in the visible region. The catalytic reactivity proved these complexes to be efficient catalysts in the oxidation of alcohols and C-C coupling. All the complexes were screened for their biocidal efficiency against bacteria such as Staphylococcus epidermidis and Escherichia coli and fungi such as Botrytis cinerea and Aspergillus niger at 0.25,0.50 and 1 % concentrations.