19926-46-6

Basic information

• Product Name: 3-phenylcyclopent-2-en-1-ol
• CAS NO: 19926-46-6
• Molecular Formula: C₁₁H₁₂O
• Molecular Weight: 160.2124
• Mol File: 19926-46-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 288.4°C at 760 mmHg
• Flash Point: 106°C
• Density: 1.134g/cm³
• Vapor Pressure: 0.00108mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 3-phenylcyclopent-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenylcyclopent-2-en-1-ol(19926-46-6)
• EPA Substance Registry System: 3-phenylcyclopent-2-en-1-ol(19926-46-6)

Safety Data

• Hazardous Substances Data: 19926-46-6(Hazardous Substances Data)

Upstream product

• 56667-10-8 (RS)-1-phenylcyclopent-2-en-1-ol 12 
• 113331-85-4 (1R^*,3R^*,4S^*)-4-phenylcyclopentane-1,3-diol 
• 591-51-5 phenyllithium 
• 114738-30-6 (3R^*,4S^*)-3-<(tert-butyldimethylsilyl)oxy>-4-phenylcyclopentan-1-one 
• 69404-97-3 2,4-pentane dione t butyl dimethyl silyl enol ether 
• 61305-35-9 4-[(tert-butyldimethylsilyl)oxy]cyclopent-2-enone 
• 51865-32-8 3-bromo-cyclopent-2-en-1-one 
• 109526-42-3 3-bromo-2-cyclopentene-1-ol 
• 98-80-6 phenylboronic acid 
• 114738-39-5 1-hydroperoxy-3-phenylcyclopent-2-ene 
• 3810-26-2 3-phenyl-2-cyclopenten-1-one 

Downstream Products

• 497158-59-5 N,O-bis(tert-butoxycarbonyl)-N-[(1R,3S)-3-phenylcyclopentyl]hydroxylamine 
• 497158-54-0 (+)-(1R,3S)-3-phenylcyclopentyl acetate 
• 497158-58-4 (+)-(1S,3S)-3-phenylcyclopentanol 
• 497158-56-2 (+)-(1R,3S)-3-phenylcyclopentol 
• 64145-51-3 (S)-3-phenylcyclopentanone 

Relevant articles and documents

1,n-rearrangement of allylic alcohols promoted by hot water: Application to the synthesis of navenone B, a polyene natural product

It was reported for the first time that hot water as a mildly acidic catalyst efficiently promoted 1,n-rearrangement (n = 3, 5, 7, 9) of allylic alcohols. In some cases, the rearrangement reactions joined isolated C-C double or triple bonds to generate conjugated polyene or enyne structure motifs. We used the 1,3-rearrangement reaction of an allylic alcohol in hot water as part of an attractive new strategy for construction of the polyene natural product navenone B by iterative use of a Grignard reaction, a 1,3-rearrangement of the resulting allylic alcohol, and subsequent oxidation of the rearranged product.

Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas

Melanin-concentrating hormone (MCH) is a cyclic, nonadecapeptide expressed in the CNS of all vertebrates that regulates feeding behavior and energy homeostasis via interaction with the central melanocortin system. Regulation of this interaction results in

Formation of 1-Phenyl-2,3-dioxabicycloheptane in the Reaction of 1,3-Dibromo-4-phenylcyclopentane with Hydrogen Peroxide in the Presence of Silver Trifluoroacetate

Reaction of 1,3-dibromo-4-phenylcyclopentane (23), prepared from 4-hydroxycyclopent-2-en-1-one (10) in a stereocontrolled manner, or its stereoisomer 24 with anhydrous hydrogen peroxide in the presence of silver trifluoroacetate in ether gave 1-phenyl-2,3-dioxabicycloheptane (25) mainly as a rearranged product.The expected 5-phenyl-2,3-dioxabicycloheptane (8) and phenylcyclopentenyl hydroperoxides 26 and 27 were also formed in this reaction.An authentic sample of endoperoxide 8 was prepared by using peroxide transfer reaction between bis(tri-n-butyltin)peroxide and bistriflate of cis-diol 35.The stereochemistry of the endoperoxide 8 and related compounds in this series was confirmed by correlation with the data from X-ray crystallographic analysis of the diacetate of diol 21 obtained from endoperoxide 8 by stannous chloride reduction.