199285-80-8Relevant academic research and scientific papers
One-pot synthesis of nitroalkenes via the Henry reaction over amino-functionalized MIL-101 catalysts
Yu, Huixian,Xie, Jianwu,Zhong, Yijun,Zhang, Fumin,Zhu, Weidong
, p. 101 - 104 (2012)
Ethylenediamine moieties with different amounts were incorporated into the metal-organic framework MIL-101 to prepare the amino-functionalized MIL-101 materials, which were used as heterogeneous catalysts in the one-pot synthesis of nitroalkenes via the Henry reaction. Various reaction conditions were optimized. Under the optimized conditions, the selectivity towards nitroalkenes is extremely high in combination with nearly complete conversion of the reactant nitroalkanes. The amino-functionalized MIL-101 behaves as a true heterogeneous catalyst, can be easily recovered by filtration, and can be reused at least twice without significant loss of its catalytic performance.
Straightforward synthesis of nitroolefins by microwave- or ultrasound-assisted Henry reaction
Rodríguez, Jose M.,Dolors Pujol
experimental part, p. 2629 - 2632 (2011/06/10)
β-Nitroalcohol or nitroethylene derivatives can be obtained from aryl aldehydes and nitromethane under Henry condensation conditions. We present a new modification using microwave irradiation or ultrasound as the energy source. Microwave irradiation allowed a novel one-pot synthesis of nitroolefins from aryl aldehydes using ammonium acetate as a catalyst without solvent. Different reaction conditions, such as base, solvent, and reaction time were studied. Only small amounts of β-hydroxyl nitro compounds were isolated, using microwave irradiation for less than 25 min. In contrast, the use of ultrasound increased the yield of the nitroalcohols.
