199296-94-1Relevant academic research and scientific papers
An experimental and computational comparison of phosphorus-and selenium-based ligands for catalysis
Ritch, Jamie S.,Charette, Bronte J.
, p. 386 - 391 (2016)
To compare and contrast the bonding and reactivity of organoselenium ligands with organophosphines in coordination complexes, a new palladium(II) complex of the Se,N-chelating ligand o-(NH2)(X)C6H4 (X = SePh, 2) was prepared. Its characterization by NMR spectroscopy, single-crystal X-ray diffraction, and density functional theory calculations is contrasted with the PdII complex of the related P,N-chelating ligand (X = PPh2, 1). These techniques indicate that the phenylseleno moiety is a weaker σ donor to the PdCl2 fragment than the diphenylphosphino group. Both complexes were suitable to catalyze the Suzuki-Miyaura coupling of p-tolylboronic acid and 4-bromobenzaldehyde.
Synthesis of platinum(II) and palladium(II) complexes containing substituted (2-aminophenyl)phosphines. Molecular structure of cis-[PtMe(2-HNC6H4PPh2)(2-H2NC 6H4PPh2)]
Chatterjee, Swarup,Hockless, David C. R.,Salem, Geoffrey,Waring, Paul
, p. 3889 - 3895 (2007/10/03)
Bis(unidentate ligand)platinum(II) complexes of the type cis-[PtMe2L2] (where L = 2-H2NC6H4PPhR and R = H, Me or Ph) were readily formed upon reaction of [PtMe2(cod)] (cod = cycloocta-1,5-diene) with L in n-pentane. The neutral ligand L is co-ordinated via the phosphorus donor atom. The complex cis-[PtMe2(2-H2NC6H4PPh 2)2] underwent a novel, facile rearrangement in benzene to give cis-[PtMe(2-HNC6H4PPh2)(2-H2NC 6H4PPh2)] with concomitant loss of methane. The molecular structure of the demethylated complex has been confirmed by an X-ray analysis. Mono(bidentate ligand)platinum(II) complexes of the type [PtCl(Me)L] (where L = 2-H2NC6H4-PPhR and R = Me or Ph) have been prepared by treating the appropriate ligand with [PtCl(Me)(cod)] in dichloromethane. Further reaction with HCl gave the dichloroplatinum(II) complexes [PtCl2L]. Substitution of the chloro groups in [MCl2L] (where M = PdII or PtII, L = 2-H2NC6H4PPhR and R = Me or Ph) can be achieved by reaction with silver nitrate in acetonitrile followed by the addition of sodium oxalate to give the complexes [M(C2O4)L]. These mono(bidentate ligand) complexes are seen as potential anticancer agents. Preliminary biological studies have shown them to be active against the mouse tumour model P815 in vitro with cytotoxicities of certain of these complexes being comparable to that of cisplatiri, cis-[PtCl2(NH3)2].
