19932-87-7

Usage

Uses

Used in Organic Synthesis:
2(3H)-Benzoxazolone, 6-Iodois used as a building block in organic synthesis for the creation of complex organic molecules. Its unique structure and reactivity, particularly due to the presence of the iodo group, make it a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2(3H)-Benzoxazolone, 6-Iodois utilized as a key intermediate in the development of new drugs. Its chemical properties allow for the formation of various bioactive compounds with potential therapeutic applications, including the treatment of diseases such as cancer, inflammation, and infectious diseases.
Used in Materials Science:
2(3H)-Benzoxazolone, 6-Iodois employed in materials science for the development of novel materials with specific properties. Its unique structure and reactivity can contribute to the creation of materials with improved performance characteristics, such as enhanced stability, conductivity, or optical properties, for use in various applications, including electronics, sensors, and coatings.
Used as a Reagent in Chemical Reactions:
2(3H)-Benzoxazolone, 6-Iodoserves as a reagent in various chemical reactions, facilitating the synthesis of target compounds. Its reactivity, especially the iodo group, can be exploited in reactions such as cross-coupling, substitution, and addition reactions, enabling the formation of a wide range of chemical products for diverse applications.

Upstream product

• 59-49-4 2-Benzoxazolinone 
• 19932-85-5 6-bromobenzo[d]oxazol-2(3H)-one 
• 606-21-3 1-chloro-2,6-dinitrobenzene 
• 81900-93-8 4-amino-2-benzoxazolone 
• 28955-71-7 4-nitrobenzo[d]oxazol-2(3H)-one 
• 573-56-8 2,6-dinitrophenol 
• 603-87-2 2-amino-6-nitrophenol 
• 16870-28-3 4-iodosalicylic acid 

Downstream Products

• 497084-49-8 6-iodo-8-quinolinol 
• 876346-93-9 C₁₁H₁₄INO₃ 

Relevant academic research and scientific papers

Method for synthesizing benzoxazole compound by using nitration by-products of aromatic hydrocarbon and application of benzoxazole compound

The invention discloses a method for synthesizing a benzoxazole compound by using nitration by-products of aromatic hydrocarbon and application of the benzoxazole compound. The method comprises the main process: performing step-by-step crystallization on nitration products of a 2,4-dinitrochlorobenzene production enterprise so as to obtain 2,4-dinitrochlorobenzene, 2,6-dinitrochlorobenzene (I) anda small amount of residues, adopting the obtained 2,6-dinitrochlorobenzene (I) as the main starting material, and performing hydrolysis, selective catalytic hydrogenation reduction, cyclization, halogenation, carbon-carbon coupling and other processes so as to synthesize the benzoxazole compound, wherein the obtained compound can be used as a main raw material to synthesize a series of chemical intermediates with important application, and the chemical intermediates include o-aminophenol, 2-amino-4-nitrophenol, 2-amino-5-nitrophenol and hydrochloride of o-aminophenol, 2-amino-4-nitrophenol, 2-amino-5-nitrophenol. Through the method, the industrial by-products are converted into high value-added aromatic aminophenol products, industrial hazardous waste of the 2,4-dinitrochlorobenzene production enterprise is reduced, the scope of products of the enterprise is widened, and the economic benefits of enterprise are increased.

ANTIBACTERIAL HETEROCYCLIC DERIVATIVES

The invention relates to antibacterial compounds of formula (I), wherein R1, M, R2, R3, and V are as described in the description, to their preparation, to salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as antibacterial agents.

METHODS FOR TREATING HEPATITIS C

In accordance with the present invention, compounds that inhibit viral replication, preferably Hepatitis C Virus (HCV) replication, have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the treatment

HIV INHIBITING 1,2,4-TRIAZIN-6-ONE DERIVATIVES

The present invention relates to HIV replication inhibitors of formula (I) a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine or a stereochemically isomeric form thereof, wherein ring A and ring B represent phenyl, pyridyl, pyridaz

Preparation and antifungal activity of 3-Iodo- and 6-Iodo-8-quinolinols

3-Iodo- and 6-Iodo-8-quinolinols were prepared and tested against six fungi: Aspergillus niger, A. oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton mentagrophytes in Sabouraud dextrose broth. A comparison with the previously known 5-iodo- and 7-iodo-8-quinolinols showed that the 6-iodo isomer was the most active.