199391-39-4

Basic information

• Product Name: 1-Chloro-4-(2,2-diethoxy-ethoxy)-2-methyl-benzene
• CAS NO: 199391-39-4
• Molecular Weight: 258.745
• Mol File: 199391-39-4.mol

Chemical Properties

• CAS DataBase Reference: 1-Chloro-4-(2,2-diethoxy-ethoxy)-2-methyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-4-(2,2-diethoxy-ethoxy)-2-methyl-benzene(199391-39-4)
• EPA Substance Registry System: 1-Chloro-4-(2,2-diethoxy-ethoxy)-2-methyl-benzene(199391-39-4)

Safety Data

• Hazardous Substances Data: 199391-39-4(Hazardous Substances Data)

Upstream product

• 59-50-7 4-Chloro-3-methylphenol 
• 621-62-5 chloroacetaldehyde diethyl acetal 

Relevant articles and documents

Bronchodilator and Antiulcer Phenoxypyrimidinones

Series of 5-phenoxy-2(1H)-pyrimidinones, 5-phenoxy-4(3H)-pyrimidinones, and related compounds were prepared in a follow-up of a lead prepared as a potential cyclic nucleotide regulating agent.Compounds were evaluated for bronchodilator activity in histamine-challenged guinea pigs and for antiulcer activity in a cold-restraint, stressed rat ulcer model.Bronchodilator activity comparable to, or greater than, that of theophylline was found in both the 2(1H)- and 4(3H)-pyrimidinone series and was most prominent in analogues containing either an electron-withdrawing or -donating substituent in the para position of the phenoxy ring.Significant antiulcer activity was observed only in the 2(1H)-pyrimidinone series among three closely related analogues.One of these, 5-(m-methylphenoxy)-2(1H)-pyrimidinone (3), exhibited more potent antiulcer effects than the clinically useful antiulcer agent carbenoxolone, without demonstrating bronchodilator activity.