199434-08-7

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 37129-23-0 ethyl 3-phenyl-1H-indole-2-carboxylate 

Relevant academic research and scientific papers

Regiospecific functionalization of indole-2-carboxylates and diastereoselective preparation of the corresponding indolines

The N-acyl derivatives of 3-substituted indole-2-carboxylates prepared through several routes were submitted to catalytic hydrogenation affording either cis- or trans-indoline diastereomers after quantitative C-2 epimerization.

Synthesis of 3-phenylindoline-2-carboxamides as semi-rigid phenylalanine mimetics

Regioselective catalytic hydrogenation of N-acyl 3-phenylindole-2-carboxylates is the key step for tile preparation of cis and trans ndoline-2-carboxamides which can be considered as phenylalanine semi-rigid derivatives.