199435-31-9

Basic information

• Product Name: 3,5-dimethyl-N-(4-methoxybenzylidene)aniline
• Synonyms: 3,5-dimethyl-N-(4-methoxybenzylidene)aniline
• CAS NO: 199435-31-9
• Molecular Weight: 239.317
• Mol File: 199435-31-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,5-dimethyl-N-(4-methoxybenzylidene)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dimethyl-N-(4-methoxybenzylidene)aniline(199435-31-9)
• EPA Substance Registry System: 3,5-dimethyl-N-(4-methoxybenzylidene)aniline(199435-31-9)

Safety Data

• Hazardous Substances Data: 199435-31-9(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 108-69-0 3,5-dimethylaminoaniline 

Downstream Products

• 619319-75-4 N-(p-methoxybenzyl)-3,5-dimethylchloroacetanilide 
• 346725-03-9 N-(p-methoxybenzyl)-3,5-dimethyl aniline 

Relevant articles and documents

Diastereoselective, multicomponent access to trans-2-aryl-4-arylamino-1,2, 3,4-tetrahydroquinolines via an AA′BC sequential four-component reaction and their application to 2-arylquinoline synthesis

The CAN-catalyzed reaction between 3,5-disubstituted anilines, vinyl ethers and aromatic aldehydes leads to trans-2-aryl-4-arylaminotetrahydroquinolines, in an AA′BC sequential multicomponent transformation related to the Povarov reaction that was also extended to the use of a second aniline as the C-4 substituent. The unusual trans stereochemistry was explained by stabilization of the corresponding intermediate by intramolecular hydrogen bonding. The presence of the 4-anilino substituent allowed adapting the method to the synthesis of 4-unsubstituted 2-arylquinolines, by treatment of the crude product from the MCR with FeCl3 in methanol.