199465-66-2 Usage
Uses
Used in Pharmaceutical Industry:
2-Cyanobenzylzinc bromide is used as a reactant for the synthesis of complex organic molecules, which are essential in the development of new pharmaceutical compounds. Its application in metal-catalyzed Negishi cross-coupling reactions allows for the preparation of aryl or heteroaryl derivatives via carbon-carbon bond formation, which are crucial for the creation of novel drug candidates.
Used in Chemical Research:
In the field of chemical research, 2-Cyanobenzylzinc bromide is used as a key reactant for the synthesis of various organic compounds. Its ability to participate in cross-coupling reactions enables the creation of new molecules with potential applications in various industries, including materials science, agrochemicals, and specialty chemicals.
Used in the Synthesis of Specific Compounds:
2-Cyanobenzylzinc bromide is used as a reactant for the preparation of specific compounds, such as 4-(2-Cyanobenzyl)-3′-(trifluoromethyl)biphenyl and 2-[(2-cyanophenyl)methyl] benzamide. These compounds are synthesized by reacting with aryl nonaflate and 2-iodobenzamide, respectively, in the presence of palladium and nickel catalysts. The resulting products have potential applications in various fields, including pharmaceuticals and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 199465-66-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,4,6 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 199465-66:
(8*1)+(7*9)+(6*9)+(5*4)+(4*6)+(3*5)+(2*6)+(1*6)=202
202 % 10 = 2
So 199465-66-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H6N.BrH.Zn/c1-7-4-2-3-5-8(7)6-9;;/h2-5H,1H2;1H;/q-1;;+2/p-1/rC8H6N.BrZn/c1-7-4-2-3-5-8(7)6-9;1-2/h2-5H,1H2;/q-1;+1
199465-66-2Relevant academic research and scientific papers
Abdiaj, Irini,Fontana, Alberto,Gomez, M. Victoria,de la Hoz, Antonio,Alcázar, Jesús
, p. 8473 - 8477 (2018)
The merging of photoredox and transition-metal catalysis has become one of the most attractive approaches for carbon–carbon bond formation. Such reactions require the use of two organo-transition-metal species, one of which acts as a photosensitizer and t
COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION
-
Paragraph 0257; 0289, (2022/03/09)
The present disclosure relates generally to compounds and pharmaceutical compositions for the selective inhibition of histone lysine demethylase5 (KDM5), particularly KDM5B, and methods of their use in treating conditions and diseases associated with KDM5 activity.
