199474-00-5Relevant academic research and scientific papers
Synthesis of [1]benzopyrano[2,3-b]pyrrol-4(1H)-ones
Alberola, Angel,Alvaro, Rocio,Ortega, Alfonso Gonzalez,Sanudo, Carmen
, p. 16185 - 16194 (1997)
2-N-(Acylmethyl)aminochromones were prepared from 2-chlorochromone and α-amino ketones (hydrochloride or ketal derivatives) in ethanol/triethylamine. Their treatment with-acetic acid/pyrrolidine led to [l]benzopyrano[2,3-b]pyrrol-4(1H)-ones, which were subsequently functionalized in C2 by aromatic electrophilic substitution (acetylation, bromination or nitration).
