199480-60-9Relevant academic research and scientific papers
The synthesis of 2′-C-functionalised nucleosides for incorporation into catalytic RNA
Lawrence, Anthony J.,Pavey, John B.J.,O'Neil, Ian A.,Cosstick, Richard
, p. 1497 - 1501 (1997)
Five 2′-C-functionalized nucleosides (1-5) have been prepared and incorporated into dinucleoside monophosphates. The effect of the functionality on the stability of the adjacent phosphodiester bond toward hydrolysis by nuclease enzymes and extremes of pH has been assessed. Copyright
