The synthesis of 2′-C-functionalised nucleosides for incorporation into catalytic RNA

Article abstract of DOI:10.1080/07328319708006215

Five 2′-C-functionalized nucleosides (1-5) have been prepared and incorporated into dinucleoside monophosphates. The effect of the functionality on the stability of the adjacent phosphodiester bond toward hydrolysis by nuclease enzymes and extremes of pH has been assessed. Copyright

Full text of DOI:10.1080/07328319708006215

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Nucleosides and Nucleotides
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The Synthesis of 2′-C-Functionalised
Nucleosides for Incorporation into
Catalytic RNA
Anthony J. Lawrence a , John B. J. Pavey a , Ian A. O'Neil a
Richard Cosstick a
&
a Robert Robinson Labs., Dept. of Chemistry , University of
Liverpool , P. O. Box 147, Liverpool, L69 3BX, U. K.
Published online: 16 Aug 2006.
To cite this article: Anthony J. Lawrence , John B. J. Pavey , Ian A. O'Neil & Richard Cosstick
(1997) The Synthesis of 2′-C-Functionalised Nucleosides for Incorporation into Catalytic RNA,
Nucleosides and Nucleotides, 16:7-9, 1497-1501, DOI: 10.1080/07328319708006215
To link to this article: http://dx.doi.org/10.1080/07328319708006215
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