199522-03-7

Upstream product

• 199522-02-6 [9-(2-Chloro-ethyl)-9H-purin-6-yl]-(9-phenyl-9H-xanthen-9-yl)-amine 
• 19255-48-2 9-(2-chloroethyl)adenine 
• 66224-66-6 adenine 
• 186342-07-4 9-N-(2'-chloroethyl)-6-N-dimethoxytrityladenine 

Relevant academic research and scientific papers

A novel class of 4'-aza analogues of 2',3'-dideoxynucleosides as potential anti-HIV drugs

The 1,3 dipolar cycloaddition approach represents the most valuable strategy for the preparation of isoxazolidine nucleosides. The latter posses more conformational degrees of freedom than the corresponding dideoxyribosides. Side reactions due to the presence of formaldehyde in the reaction media can be avoided by proper derivatization of the vinyl- nucleobase.