199532-89-3Relevant academic research and scientific papers
Diastereoselective synthesis of cyclopentanoids with hydantoin and isoxazoline substituents
Park, Kyung-Ho,Olmstead, Marilyn M.,Kurth, Mark J.
, p. 113 - 117 (2007/10/03)
Exploiting 1,3-dipolar cycloaddition and urea → hydantoin cyclization transformations, novel spiro-[cyclopenta[d]isoxazole-4'5-imidazolindine' heterocycles of generalized structure I have been prepared. The 1-amino-3- cyclopentenecarboxylate precursor II was prepared from a suitably activated/protected derivative of glycine and the bis-alkylating agent cis- 1,4-dichloro-2-butene.
