199581-55-0Relevant academic research and scientific papers
An efficient multigram synthesis of monomers for the preparation of novel oligonucleotides containing isosteric non-phosphorous backbones
Dimock, Stuart,Bhat, Balkrishen,Peoc'h, Didier,Sanghvi, Yogesh S.,Swayze, Eric E.
, p. 1629 - 1632 (2007/10/03)
The facile preparation of two novel classes of nucleoside analogs for the inclusion as dimeric non-phosphorous containing subunits in chime fie backbones has been accomplished. The concise preparation of 3'- formylnucleosides and 5'-O-(N-methylhydroxylamino)-nucleosides is reported.
A mild and highly selective N-benzoylation of cytosine and adenine bases in mucleosides with N-benzoyltetrazole
Bhat, Balkrishen,Sanghvi, Yogesh S.
, p. 8811 - 8814 (2007/10/03)
N-Benzoyltetrazole has been developed as a mild and selective reagent for monobenzoylation of the exocyclic amino group in nucleic acid bases. Its usefulness is demonstrated by protection of adenine and cytosine bases, an important procedure in the nucleic acid chemistry field.
