19959-63-8Relevant academic research and scientific papers
PIDA-Mediated Formal Olefinic C=C Bond Cleavage of α-Oxo-Ketene N,N-Acetals toward Substituted Oxazolines
Guo, Tenglong,Huang, Fei,Jiang, Quanbin,Yu, Zhengkun
supporting information, p. 14368 - 14372 (2018/09/14)
The hypervalent iodine reagent PhI(OAc)2 (PIDA) mediated the formal oxidative C=C bond cleavage and subsequent cyclization of internal olefins, that is, α-oxo-ketene N,N-acetals, which afforded substituted oxazolines. Isothiazoline derivatives were obtained from the reactions of α-thioxo-ketene N,N-acetals with PIDA under the same conditions. Hydrolysis of the resultant oxazoline derivatives led to highly functionalized oxazolones. A plausible mechanism was proposed based upon the formation of isothiazoline-type intermediates.
STUDIES ON LEAD TETRAACETATE OXIDATION OF α-OXOKETENE S,N- AND N,N-ACETALS
Thomas, Abraham,Vishwakarma, Jai N.,Apparao, Satyam,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar
, p. 1667 - 1672 (2007/10/02)
Lead tetraacetate oxidation of α-oxoketene-S,N-phenyl (1a) and S,N-benzyl (1b) acetals gave the iminoacetate 2 and α-acetoxy-S,N-acetal 3 respectively, while the corresponding S,N-ethylacetal 1c yielded the iminodiacetate 5.The corresponding N,N-arylaceta
