199608-48-5

Basic information

• Product Name: 4-bromo-2,5-dichloroacetanilide
• Synonyms: 4-bromo-2,5-dichloroacetanilide
• CAS NO: 199608-48-5
• Molecular Weight: 282.952
• Mol File: 199608-48-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-bromo-2,5-dichloroacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2,5-dichloroacetanilide(199608-48-5)
• EPA Substance Registry System: 4-bromo-2,5-dichloroacetanilide(199608-48-5)

Safety Data

• Hazardous Substances Data: 199608-48-5(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 113571-16-7 4-Bromo-2,3-dichloroacetanilide 
• 64-19-7 acetic acid 
• 71-43-2 benzene 
• 103-88-8 4-bromoacetanilide 
• 95-82-9 2,5 dichloroaniline 
• 108-24-7 acetic anhydride 
• 22459-81-0 N-(4-bromo-3-chlorophenyl)acetamide 

Downstream Products

• 1435-50-3 2-bromo-1,4-dichlorobenzene 
• 1940-27-8 2,5-dichloro-4-bromo-aniline 

Relevant articles and documents

Complementary Site-Selective Halogenation of Nitrogen-Containing (Hetero)Aromatics with Superacids

Site-selective functionalization of arenes that is complementary to classical aromatic substitution reactions remains a long-standing quest in organic synthesis. Exploiting the generation of halenium ion through oxidative process and the protonation of the nitrogen containing function in HF/SbF5, the chlorination and iodination of classically inert Csp2?H bonds of aromatic amines occurs. Furthermore, the superacid-promoted (poly)protonation of the molecules acts as a protection, favoring the late-stage selective halogenation of natural alkaloids and active pharmaceutical ingredients.