199682-74-1

Basic information

• Product Name: 5-(2-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE
• Synonyms: 5-(2-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE
• CAS NO: 199682-74-1
• Molecular Formula: C10H7ClN2O
• Molecular Weight: 206.63
• Mol File: 199682-74-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 424.3±35.0 °C(Predicted)
• Appearance: /
• Density: 1.378±0.06 g/cm3(Predicted)
• PKA: 10.28±0.50(Predicted)
• CAS DataBase Reference: 5-(2-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE(199682-74-1)
• EPA Substance Registry System: 5-(2-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE(199682-74-1)

Safety Data

• Hazardous Substances Data: 199682-74-1(Hazardous Substances Data)

Usage

General Description

5-(2-chlorophenyl)-1H-pyrazole-4-carbaldehyde is a chemical compound with a molecular formula C10H7ClN2O. It is a pyrazole compound with a carbaldehyde group and a chlorophenyl substituent. This chemical is primarily used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds. It may have potential applications in medicinal chemistry and drug discovery. However, further research is needed to fully understand its properties and potential uses.

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Relevant articles and documents

Synthesis and evaluation of antimicrobial and anticancer activities of 3-phenyl-1-phenylsulfonyl pyrazoles containing an aminoguanidine moiety

A series of 3-phenyl-1-phenylsulfonyl pyrazoles containing an aminoguanidine moiety was designed, synthesized, and evaluated for their antimicrobial and anticancer activities. The majority of the target compounds showed broad-spectrum antimicrobial activi

A new synthethic approach to indazole synthesis

Stobbe condensation of 3-alkyl- or aryl-4-formylpyrazoles 3a-f with diethyl succinate in the presence of potassium f-butoxide, followed by intramolecular ring closure (Ac2O-NaOAc), afforded the corresponding indazole derivatives 5a-f in 65-85% overall yield. These compounds are good starting materials for transformation to biologically active molecules, such as new pyrazole analogs of the left-hand segment of the potent natural antineoplastic agent CC-1065.