199800-56-1

Basic information

• Product Name: 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N⁶-phthaloylcytidine
• Synonyms: 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N⁶-phthaloylcytidine
• CAS NO: 199800-56-1
• Molecular Weight: 659.695
• Mol File: 199800-56-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N⁶-phthaloylcytidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N⁶-phthaloylcytidine(199800-56-1)
• EPA Substance Registry System: 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N⁶-phthaloylcytidine(199800-56-1)

Safety Data

• Hazardous Substances Data: 199800-56-1(Hazardous Substances Data)

Upstream product

• 88-95-9 Phthaloyl dichloride 
• 51432-42-9 4-Amino-1-((2R,4S,5R)-4-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 199800-43-6 2'-deoxy-N⁶-phthaloylcytidine 

Downstream Products

• 76512-82-8 5'-O-(4,4'-dimethoxytrityl)deoxycytidine 

Relevant articles and documents

Phthaloyl strategy - A new approach towards oligodeoxyribonucleotide synthesis

A new rapid strategy for machine-aided oligodeoxyribonucleotide synthesis has been established utilizing phthaloyl groups for protection of the heterocyclic amino functions within the phosphoramidite approach. A large number of DNA-sequences has been synt

Nucleotides: Part LXI: Phthaloyl strategy: A new concept of oligonucleotide synthesis

A new alternative strategy of oligonucleotide synthesis was developed by use of the phthaloyl protecting group for the exocyclic amino functions of the nucleobases (see 9-12). This approach combines the advantages of cheap and easily accessible monomeric building blocks (see 17- 20), standard machine-aided oligonucleotide synthesis, and a fast deprotection protocol which is orthogonal to the cleavage procedure from the solid support. The crude oligonucleotides show high purity and require, in general, no further chromatographic purification.