19983-18-7 Usage
Description
2-Pyrrolidino-thiophene, with the molecular formula C8H11NS, is a heterocyclic aromatic compound belonging to the class of organic compounds. It is a derivative of thiophene, characterized by a five-membered ring with four carbon atoms and one sulfur atom. 2-PYRROLIDINO-THIOPHENE is recognized for its versatile reactivity and biological activity, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, dyes, and pigments. Its unique structure and properties contribute significantly to the field of organic chemistry and various industrial applications.
Uses
Used in Pharmaceutical Industry:
2-Pyrrolidino-thiophene is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to enhance the biological activity of the final products. Its incorporation into drug molecules can improve their efficacy, selectivity, and pharmacokinetic properties, leading to the development of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Pyrrolidino-thiophene serves as a crucial building block for the synthesis of agrochemicals, such as insecticides, herbicides, and fungicides. Its versatile reactivity allows for the creation of compounds with improved pesticidal properties, contributing to more effective and targeted crop protection.
Used in Dye and Pigment Production:
2-Pyrrolidino-thiophene is utilized as a starting material in the production of dyes and pigments due to its unique chromophoric properties. Its incorporation into dye molecules results in a wide range of colors and improved colorfastness, making it suitable for various applications, including textiles, plastics, and printing inks.
Used in Organic Chemistry Research:
As a heterocyclic aromatic compound, 2-Pyrrolidino-thiophene is a valuable compound in organic chemistry research. Its unique structure and reactivity make it an ideal candidate for studying various organic reactions, such as electrophilic substitution, nucleophilic addition, and cycloaddition. This research contributes to the understanding of reaction mechanisms and the development of new synthetic methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 19983-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,8 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19983-18:
(7*1)+(6*9)+(5*9)+(4*8)+(3*3)+(2*1)+(1*8)=157
157 % 10 = 7
So 19983-18-7 is a valid CAS Registry Number.
19983-18-7Relevant articles and documents
Fluorescent bithiophene chromophores: synthesis and application in cd exciton chirality studies
Ikemoto, Norihiro,Estevez, Isabel,Nakanishi, Koji,Berova, Nina
, p. 489 - 501 (1997)
Bithiophene chromophores were synthesized and used to derivatize NH2 and OH groups in aminocyclohexane, (1R, 2R)-diaminocyclohexane, (1R, 2R)-trans-1,2-cyclohexanediol and methyl L-acosamidine for their application in the exciton chirality method. Schiff base, ester and amide derivatives were generated in good yields and were found to exhibit exciton-split CD curves. Besides their absorption at long wavelengths (red-shifted) in the visible range, the bithiophene derivatives showed fluorescence and solvatochromic properties.
A mild and practical copper catalyzed amination of halothiophenes
Lu, Zhikuan,Twieg, Robert J.
, p. 903 - 918 (2007/10/03)
We have found that N,N-dimethylethanolamine (deanol) is a useful solvent and ligand for copper catalyzed amination of a variety of unactivated and activated 2- or 3-halothiophenes. Primary amines, acyclic secondary amines, cyclic secondary amines and acyclic secondary amines with 2-hydroxyethyl functionality react with halothiophenes in moderate to excellent yields. The mildly basic conditions utilized are compatible with many functional groups. The amination of halobithiophenes has also been examined. The aminothiophenes produced by this method are important intermediates in a variety of electronic and optoelectronic materials. We have found that N,N-dimethylethanolamine (deanol) is a useful solvent and ligand for copper catalyzed amination of a variety of unactivated and activated 2- or 3-halothiophenes. Primary amines, acyclic secondary amines, cyclic secondary amines and acyclic secondary amines with 2-hydroxyethyl functionality react with halothiophenes providing the corresponding aminated thiophenes in moderate to excellent yields. The mildly basic conditions utilized are compatible with many functional groups. The amination of halobithiophenes has also been examined. The aminothiophenes produced by this method are important intermediates in a variety of electronic and optoelectronic materials.
