199934-50-4

Basic information

• Product Name: (E)-2-(3-oxoprop-1-en-1-yl)phenyl benzoate
• Synonyms: (E)-2-(3-oxoprop-1-en-1-yl)phenyl benzoate
• CAS NO: 199934-50-4
• Molecular Weight: 252.269
• Mol File: 199934-50-4.mol

Chemical Properties

• CAS DataBase Reference: (E)-2-(3-oxoprop-1-en-1-yl)phenyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(3-oxoprop-1-en-1-yl)phenyl benzoate(199934-50-4)
• EPA Substance Registry System: (E)-2-(3-oxoprop-1-en-1-yl)phenyl benzoate(199934-50-4)

Safety Data

• Hazardous Substances Data: 199934-50-4(Hazardous Substances Data)

Upstream product

• 6362-81-8 2-allylphenyl benzoate 
• 51764-86-4 2-hydroxycinnamyl alcohol 
• 6236-69-7 methyl 2-hydroxycinnamate 
• 614-60-8 o-Coumaric acid 
• 60125-23-7 (E)-3-(2-hydroxyphenyl)propenal 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Inhibition of human tumor growth by 2'-hydroxy- and 2'- benzoyloxycinnamaldehydes

2'-Hydroxycinnamaldehyde (HCA) was isolated from Cinnamomum cassia Blume (Lauraceae) and 2'-benzoyloxycinnamaldehyde (BCA) was prepared by the reaction of HCA and benzoyl chloride. HCA and BCA strongly inhibited in vitro growth of 29 kinds of human cancer

Modular synthesis of (E)-cinnamaldehydes directly from allylarenes via a metal-free DDQ-mediated oxidative process

An efficient synthesis of (E)-cinnamaldehydes by a metal-free DDQ-mediated oxidative transformation of allylarenes was developed. The protocol provides a practical method to prepare diverse (E)-cinnamaldehydes with broad functional group tolerance in good to excellent yields, including easy access to natural products randainal and geranyloxy sinapyl aldehyde from plant extracts. Finally, the mechanism of a single-electron transfer process was proposed.

Composition for preventing cancer comprising 2'-benzoyl-oxycinnamaldehyde

Disclosed is a composition for preventing cancer comprising a compound represented by Chemical Formula 1, 2′-benzoyloxycinnamaldehyde (BCA). BCA has the effects of delaying tumor incidence and increasing immune cells in a transgenic mouse overexpressing H-ras oncogene playing a critical role in tumor cell growth. Thus, BCA is useful as a cancer preventive drug.

COMPOSITION FOR PREVENTING CANCER COMPRISING 2'-BENZOYL-OXYCINNAMALDEHYDE

Disclosed is a composition for preventing cancer comprising a compound represented by Chemical Formula 1, 2??-benzoyloxycinnamaldehyde (BCA). BCA has the effects of delaying tumor incidence and increasing immune cells in a transgenic mouse overexpressing H-ras oncogene playing a critical role in tumor cell growth. Thus, BCA is useful as a cancer preventive drug.

Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1

A series of cinnamaldehydes was synthesized for the study of inhibitory activity against cyclin dependent kinases (CDKs). A couple of compounds selectively inhibited cyclin D1-CDK4 with an IC50 value of 7-18 μM. (C) 2000 Elsevier Science Ltd. All rights reserved.