20000-80-0

Basic information

• Product Name: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-1-ETHANOL
• Synonyms: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-1-ETHANOL;AKOS B023994;AKOS PAO-0964;AKOS BBS-00005323;ART-CHEM-BB B023994;3,5-DiMethyl-1-(2-hydroxyethyl)pyrazole;2-(3,5-dimethylpyrazol-1-yl)ethanol
• CAS NO: 20000-80-0
• Molecular Formula: C₇H₁₂N₂O
• Molecular Weight: 140.18
• Mol File: 20000-80-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 61-64°C
• Boiling Point: 252°Cat760mmHg
• Flash Point: 106.2°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 0.0104mmHg at 25°C
• Refractive Index: 1.535
• PKA: 14.47±0.10(Predicted)
• CAS DataBase Reference: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-1-ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-1-ETHANOL(20000-80-0)
• EPA Substance Registry System: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-1-ETHANOL(20000-80-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 20000-80-0(Hazardous Substances Data)

Usage

General Description

2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-1-ETHANOL is a chemical compound with the molecular formula C9H14N2O. It is a pyrazole derivative with a hydroxyl group attached to the ethyl chain. 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-1-ETHANOL has potential applications in the field of pharmaceuticals and organic synthesis. It may be used as a building block in the synthesis of various drugs or as a reagent in organic chemical reactions. Its specific properties and potential uses make it a subject of interest for researchers and chemists in the pursuit of new drug discovery and chemical synthesis methods.

InChI:InChI=1/C7H12N2O/c1-6-5-7(2)9(8-6)3-4-10/h5,10H,3-4H2,1-2H3

Upstream product

• 109-84-2 2-hydroxyethylhydrazine 
• 123-54-6 acetylacetone 
• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 540-51-2 2-bromoethanol 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 67000-34-4 2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl 4-methylbenzenesulfonate 
• 866550-22-3 2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl diphenylphosphinite 
• 1083152-90-2 1,2-bis[4-(3,5-dimethyl-1H-pyrazol-1-yl)-2-oxabutyl]benzene 
• 1093207-57-8 2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)ethoxy)-6-nitrobenzonitrile 
• 1052561-82-6 1-(2-hydroxyethyl)-3,5-dimethylpyrazole-4-carboxylic acid 
• 1038394-02-3 2-(3,5-diphenyl-1H-pyrazol-1-yl)ethyldiphenylphosphinite 
• 1083152-92-4 1,4-bis[4-(3,5-dimethyl-1H-pyrazol-1-yl)-2-oxabutyl]benzene 

Relevant articles and documents

Synthesis and oxidation of some azole-containing thioethers

Pyrazole and benzotriazole-containing thioethers, namely 1,5-bis(3,5-dimethylpyrazol-1-yl)-3-thiapentane, 1,8-bis(3,5- dimethylpyrazol-1-yl)-3,6-dithiaoctane and 1,3-bis(1,2,3-benzotriazol-1-yl)-2- thiapropane were prepared and fully characterized. Oxidat

Solvent-free synthesis of 3,5-di-tert-butylpyrazole and 3,5-di-substitutedbutylpyrazol-1-ylethanol

A high-yield, solvent-free approach to the synthesis of 1,3,5-trisubstituted pyrazoles is reported. Four compounds, (3,5-di-tert-butyl- 1H-pyrazole, (2-(3,5-dimethyl-1H-pyrazol-1-yl)ethanol, 2-(3,5-di-tert-butyl-1H- pyrazol-1-yl)ethanol, 2-(3,5-diphenyl-1

Asymmetric borane reduction of ketones catalyzed by N-hydroxyalkyl-l-menthopyrazoles

The equimolar mixture of N-(hydroxyalkyl)pyrazoles and borane formed boric ester complex, in which the remaining borane was stabilized by the adjacent nitrogen of thr pyrazole ring. The borane complex derived from the chiral pyrazoles such as 3-phenyl-l-menthopyrazole reduced p-methylacetophenone (21) enantioselectively. When (2'S)-2-(2'-phenyl-2'-hydroxyethyl)-3-phenyl-l-menthopyrazole ((2'S)-10b) was used, 21 was reduced into (S)-p-methylphenyl-1-ethanol (22) in moderate chemical and optical yields. Due to the inconvenience of the preparation and the lower optical yield, the use of N-(α-hydroxyalkyl)pyrazoles was unpromising for the enantioselective reduction of ketones by borane.