200008-68-0Relevant academic research and scientific papers
Asymmetric synthesis using catalysts containing multiple stereogenic centres and a trans-1,2-diaminocyclohexane core; Reversal of predominant enantioselectivity upon N-alkylation
Cobb, Alexander J.A.,Marson, Charles M.
, p. 1269 - 1279 (2007/10/03)
N-Methylation of ligands containing a trans-1,2-diaminocyclohexane core and multiple stereogenic centres is shown to provide the product of the opposite configuration in significant enantiomeric excess, in the addition of diethylzinc to aldehydes. Some of
Reversal of enantioselectivity using catalysts containing multiple stereogenic centres
Cobb, Alexander J. A.,Marson, Charles M.
, p. 1547 - 1550 (2007/10/03)
N-Methylation of ligands with multiple stereogenic centres is shown to provide the product of the opposite configuration in significant enantiomeric excess (e.e.), in the addition of diethylzinc to aldehydes. The catalysts possess stereogenic centres appe
Synthesis and stereochemistry of cobalt(III) complexes with the new optically active phosphine ligand, N,N′-Bis[2-(diphenylphosphanyl)ethyl]-(1R,2R)-cyclohexane-1,2-diamine (ch-PNNP). Crystal structure of Λ-cisβ-[Co(acac)(ch-PNNP)](ClO4)2
Atoh, Masamichi,Sorensen, Henning Osholm,Andersen, Peter
, p. 1169 - 1177 (2007/10/03)
A new optically active tetradentate phosphine ligand, N,N′-bis[2-(diphenylphosphanyl)ethyl]-(1R,2R)-cyclohexane-1,2-diamine (ch-PNNP), was prepared from (1R,2R)-cyclohexane-1,2-diamine and purified through the nickel(II) complex. Three new ch-PNNP complexes of cobalt(III) were prepared: trans-[CoCl2(ch-PNNP)]+, trans-[Co(NCS)2(ch-PNNP)]+ and Λ-cisβ-[Co-(acac)(ch-PNNP)]2+. The geometrical structures of the complexes were assigned on the basis of NMR, CD and absorption spectra. The molecular structure and the absolute configuration of A-cisβ-[Co(acac)(ch-PNNP)](ClO4), were determined by X-ray analysis. The orthorhombic cell (P212121) has a=12.721(4), b=17.073(3), c= 18.26(3) A, V=3966(7) A3 and Z = 4. The X-ray analysis shows that the three chelate rings from the ch-PNNP ligand form distorted gauche (δλλ) conformations. Acta Chemica Scandinavica 1997.
