20016-85-7

Usage

Uses

Used in Pharmaceutical Industry:
(R)-2-Hydroxybutyric Acid is used as a remedy for hangovers, helping to alleviate the symptoms and promote recovery. It is believed to work by increasing the body's metabolism of alcohol, thus reducing the severity and duration of hangover effects.
Used in Sports and Fitness Industry:
(R)-2-Hydroxybutyric Acid is used as a supplement to enhance physical performance and endurance. It is thought to improve energy levels and reduce fatigue during exercise, making it a popular choice among athletes and fitness enthusiasts.
Used in Research and Development:
(R)-2-Hydroxybutyric Acid is used in scientific research as a chiral building block for the synthesis of various pharmaceutical compounds. Its unique (R)-configuration allows for the development of new drugs with specific properties and applications.
Used in Cosmetics Industry:
(R)-2-Hydroxybutyric Acid may be used in the development of cosmetic products, particularly those targeting skin health and rejuvenation. Its potential benefits in this area are still being explored and researched.

InChI:InChI=1/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m1/s1

Upstream product

• 600-15-7 2-Hydroxybutanoic acid 
• 3347-90-8 (2S)-2-hydroxybutanoic acid 
• 71-36-3 butan-1-ol 
• 133964-75-7 (S)-2-Hydroxy-N-methyl-butyramide 
• 168103-92-2 (R)-2-Acetoxy-butyric acid (1R,2R)-2,3-dihydroxy-1-(hydroxy-diphenyl-methyl)-3,3-diphenyl-propyl ester 
• 89426-82-4 (1S,2S,6R,7R)-4-(1-Methoxymethoxy-propyl)-1,10,10-trimethyl-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-4-ene 

Downstream Products

• 1334671-79-2 N-benzyl (R)-2-hydroxylbutanamide 
• 600-18-0 2-Oxobutyric acid 
• 1621671-24-6 (R)-3,6-diethyl-1,4-dioxane-2,5-dione 
• 4511-42-6 L,L-dilactide 

Relevant academic research and scientific papers

Enzymatic Resolution of Chiral 2-Hydroxy Carboxylic Acids by Enantioselective Oxidation with Molecular Oxygen Catalyzed by the Glycolate Oxidase from Spinach (Spinacia oleracea)

The enzymatic oxidation of a variety of saturated and unsaturated aliphatic derivatives of racemic 2-hydroxy acids 1 to their 2-oxo acids 2 with molecular oxygen catalyzed by the glycolate oxidase from spinach (Spinacia oleracea) was shown to proceed highly enantioselectively.Thus, the glycolate oxidase-catalyzed kinetic resolution provides a convenient biocatalytic method for the preparation of enantiomerically pure (R)-2-hydroxy acids.The absolute configuration of the (R)-2-hydroxy acid 1b assigned by comparison of the measured optical rotation value with that of the literature data and by application of the exciton-coupled circular dichroism method (ECCD) on its bichromophoric 2-naphthoate 9-methylanthryl derivative 3b.These results establish the ECCD method as a convenient microscale chirooptic tool for the configurational assignment of 2-hydroxy acids.

A Novel Bicyclic Orthoester as a Chiral Auxiliary: Application to the Synthesis of α-Hydroxy Acids

Chiral α-keto orthoesters derived from tartanic acid can be reduced diastereoselectively.Hydrolysis affords optically actice α-hydroxy acids and the recovered auxiliary.

A SYNTHON FOR CHIRAL GLYCOLATE ENOLATE (ROC-HCOOR'): A CAMPHOR-BASED OXAZOLINE

Alkylations of the anion (7a) derived from a camphor-based oxazoline proceed in good yield.Hydrolysis affords the corresponding α-hydroxy acids in high ee.