200186-51-2

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 200186-50-1 C₆₀H₁₀₂O₉Si₄ 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 200186-30-7 (4R,5S,6R)-4-(4-Benzyloxy-butyl)-6-iodomethyl-5-methyl-[1,3]dioxan-2-one 
• 200186-39-6 C₅₆H₉₈O₁₀Si₃ 
• 200186-26-1 (S)-{2-[(4S,5S,6R)-6-(4-Benzyloxy-butyl)-2,2,5-trimethyl-[1,3]dioxan-4-ylmethyl]-[1,3]dithian-2-yl}-((4aR,6R,7R,8R,8aS)-8-benzyloxy-2,2,7-trimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-methanol 
• 200186-42-1 C₆₅H₁₁₀O₁₀Si₄ 
• 200186-49-8 C₄₉H₉₂O₁₀Si₃ 
• 200186-47-6 [(S)-{2-[(4S,5S,6R)-6-(4-Benzyloxy-butyl)-2,2,5-trimethyl-[1,3]dioxan-4-ylmethyl]-[1,3]dithian-2-yl}-((4aR,6R,7R,8R,8aS)-8-benzyloxy-2,2,7-trimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-methoxy]-tert-butyl-dimethyl-silane 
• 200186-48-7 2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-4-benzyloxy-6-[(S)-[(2R,4S,5R,6R)-6-(4-benzyloxy-butyl)-4-hydroxy-2-methoxy-5-methyl-tetrahydro-pyran-2-yl]-(tert-butyl-dimethyl-silanyloxy)-methyl]-3-hydroxy-5-methyl-tetrahydro-pyran-2-ylmethyl ester 
• 200186-38-5 (2S,3S,4R)-8-Benzyloxy-1-{2-[(S)-((2R,3R,4R,5S,6R)-4-benzyloxy-5-hydroxy-6-hydroxymethyl-3-methyl-tetrahydro-pyran-2-yl)-(tert-butyl-dimethyl-silanyloxy)-methyl]-[1,3]dithian-2-yl}-3-methyl-octane-2,4-diol 
• 200186-27-2 (4R,5S,6S)-4-(4-Benzyloxy-butyl)-6-[1,3]dithian-2-ylmethyl-2,2,5-trimethyl-[1,3]dioxane 
• 200186-35-2 Benzoic acid (1R,2R,3S)-2-benzyloxy-1-((R)-1,2-dihydroxy-ethyl)-3-methyl-pent-4-enyl ester 
• 200186-44-3 Carbonic acid (R)-5-benzyloxy-1-((R)-1-methyl-allyl)-pentyl ester tert-butyl ester 

Downstream Products

• 200186-25-0 C₆₀H₁₀₁IO₈Si₄ 

Relevant academic research and scientific papers

Spongistatin synthetic studies. 1. Construction of a C(29-48) subtarget

In this Letter, the first in a series of three, we outline our overall strategy and describe the assembly of a C(29-48) EF-ring advanced intermediate for the total synthesis of the spongistatins, rare and structurally unique polyether macrolides with unpr