200195-19-3

Upstream product

• 200195-14-8 4-(chloroacetyl-amino)-3-hydroxy-benzaldehyde 
• 253687-16-0 7-(hydroxymethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 142166-00-5 methyl 3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxylate 
• 713-52-0 methyl 3-hydroxy-4-nitrobenzoate 
• 200195-17-1 2-chloro-N-(4-[1,3]dioxan-2-yl-2-hydroxy-phenyl)-acetamide 
• 200195-16-0 2-(3-hydroxy-4-nitro-phenyl)-1,3-dioxane 
• 704-13-2 5-formyl-2-nitrophenol 
• 852233-77-3 ethyl 2-(5-formyl-2-nitrophenoxy)acetate 

Downstream Products

• 200195-01-3 7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one 
• 253687-19-3 7-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-4H-benz[1,4]oxazin-3-one 
• 853657-91-7 diethyl (2S)-2-{[(2S)-2-({[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl]methyl}amino)-3-phenylpropanoyl]amino}pentanedioate 
• 852233-71-7 ethyl (2S)-2-({[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl]methyl}-amino)-3-phenylpropanoate 
• 853657-90-6 (2S)-2-({[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl]methyl}amino)-3-phenyl-propanoic acid 
• 852233-78-4 4-[(7-formyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)methyl]-benzonitrile 

Relevant academic research and scientific papers

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

5-Quinoline derivatives having an anti-bacterial activity

The present invention describes novel anti-bacterial compounds of the formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase and topoisomerases, for example of topoisomerase II and IV.

Toward a novel class of antithrombotic compounds with dual function. Discovery of 1,4-benzoxazin-3(4H)-one derivatives possessing thrombin inhibitory and fibrinogen receptor antagonistic activities

A novel class of potential antithrombotic compounds with moderate thrombin inhibitory and fibrinogen receptor antagonistic activity is described. Combination of anticoagulant and antiaggregatory activity in the same molecular entity is presented as a new

ANTITHROMBOTIC COMPOUNDS WITH DUAL FUNCTION

The present invention comprises compounds of the general formula (I) : and pharmaceutically acceptable salts thereof, wherein the substituents have in the description specified meaning. The compounds are used as antithrombotic agents possessing inhibitory

Benzoxazinone dopamine D4 receptor antagonists

This invention relates to compounds that are antagonists of dopamine D4 receptors, to methods of treating psychosis and schizophrenia using a compound that is an antagonist of dopamine D4 receptors, and to pharmaceutically acceptable compositions that con

A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: Discovery of a potential atypical antipsychotic agent

As part of a program to develop dopamine D4 antagonists for the treatment of schizophrenia, we discovered a series of 6- and 7- (phenylpiperazinyl)- and -(phenylpiperidinyl)methylbenzoxazinones through mass screening of our compound library. A structure-a