253687-19-3Relevant academic research and scientific papers
A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: Discovery of a potential atypical antipsychotic agent
Belliotti, Thomas R.,Wustrow, David J.,Brink, Wouter A.,Zoski, Kim T.,Shih, Yu-Hsin,Whetzel, Steven Z.,Georgic, Lynn M.,Corbin, Ann E.,Akunne, Hyacinth C.,Heffner, Thomas G.,Pugsley, Thomas A.,Wise, Lawrence D.
, p. 5181 - 5187 (2007/10/03)
As part of a program to develop dopamine D4 antagonists for the treatment of schizophrenia, we discovered a series of 6- and 7- (phenylpiperazinyl)- and -(phenylpiperidinyl)methylbenzoxazinones through mass screening of our compound library. A structure-a
