200271-78-9

Upstream product

• 40807-61-2 4-hydroxy-4-phenylpiperidin 
• 184968-70-5 3-(3,4-dichloro-phenyl)-1-(4-hydroxy-4-phenyl-piperidin-1-yl)-pent-4-en-1-one 
• 184968-61-4 3-(3,4-di-chlorophenyl)-4-pentenoic acid 
• 184968-71-6 1-[3-(3,4-dichloro-phenyl)-pent-4-enyl]-4-phenyl-piperidin-4-ol 

Downstream Products

• 184969-61-7 3-(3,4-dichlorophenyl)-1-[[dimethyl(1,1-dimethyl-ethyl)silyl]oxy]-5-(4-hydroxy-4-phenyl-1-piperidinyl)-2-pentanone 
• 184969-59-3 β-(3,4-dichlorophenyl)-α-[[[dimethyl(1,1-dimethylethyl)silyl]oxy]-methyl]-4-hydroxy-4-phenyl-1-piperidinebutanol 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of oxime neurokinin antagonists: Discovery of potent arylamides

The structural modification of the benzylic ether region of oxime 1 has resulted in the identification of several novel aryl amides as selective or dual NK1/NK2 antagonists.