200346-57-2

Upstream product

• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 350255-13-9 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 19614-12-1 2-bromo-5-methoxybenzyl bromide 
• 200346-55-0 (R)-1-[(3aR,5R,6S,6aR)-6-(2-Bromo-5-methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-ethane-1,2-diol 

Relevant academic research and scientific papers

Stereoselective domino azidation and [3 + 2] cycloaddition: A facile route to chiral heterocyclic scaffolds from carbohydrate derived synthons

A rapid one pot intermolecular aryl azidation and intramolecular azide-olefin cycloaddition protocol has been designed using carbohydrate precursors to generate optically active, aziridine fused oxa-aza heterocycles, related to DNA targeting anti-tumour a

Synthesis of chiral cis- and trans-furo[3,2-c][2]benzoxocines from D-glucose by regioselective 8-endo aryl radical cyclisation

A simple chiral synthesis of cis- and trans-furo[3,2-c][2]benzoxocines 8a-d and 9a-d through a regioselective 8-endo-trig aryl radical cyclisation of the respective 5,6-dideoxy-D-xylo-hex-5-enofuranosides 6a-d and 5,6-dideoxy-D-ribo-hex-5-enofuranosides 7

A simple construction of chiral fused benzoxocine ring ethers from D-glucose by regioselective 8-endo-aryl radical cyclisation

A regioselective 8-endo-trig aryl radical cyclisation of the 5,6-deoxy-D-xylo-5-enofuranosides 3a and 3b with tri-n-butyltin hydride provides the chiral furo[3,2-c][2]benzoxocines 4a and 4b in good yields; the crystal structure of 4a is reported.