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2-styryl-3-(o-tolyl)quinazolin-4(3H)-one is a complex organic compound belonging to the quinazolinone class, characterized by a quinazoline core with a styryl group at the 2-position and an o-tolyl group at the 3-position. This molecule exhibits a tricyclic structure, with the styryl group introducing a phenyl ring connected to a vinyl group, and the o-tolyl group featuring a methyl substituent on the ortho position relative to the phenyl ring attached to the quinazoline. The compound has potential applications in medicinal chemistry, particularly as a scaffold for the development of new drugs, due to its unique structure and the ability to form various derivatives. Its chemical properties and reactivity are influenced by the presence of the styryl and o-tolyl groups, which can participate in different types of chemical reactions, such as electrophilic aromatic substitution and conjugation effects.

2004-80-0

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2004-80-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2004-80-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,0 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2004-80:
(6*2)+(5*0)+(4*0)+(3*4)+(2*8)+(1*0)=40
40 % 10 = 0
So 2004-80-0 is a valid CAS Registry Number.

2004-80-0Downstream Products

2004-80-0Relevant academic research and scientific papers

Synthesis of 2,3-Disubstituted Quinazolinone Derivatives through Copper Catalyzed C-H Amidation Reactions

Kotipalli, Trimurtulu,Kavala, Veerababurao,Janreddy, Donala,Bandi, Vijayalakshmi,Kuo, Chun-Wei,Yao, Ching-Fa

, p. 1182 - 1193 (2016/03/05)

The synthesis of quinazolinone derivatives was achieved from 2-iodobenzamide derivatives and various benzylamines, allylamine, and cinnamylamine derivatives through a one-pot copper-catalyzed reaction. In this reaction, the amine component (benzylamine/allylamine/cinnamylamine) is N-arylated with 2-iodobenzamide derivatives through Ullman coupling, followed by an intramolecular C-H amidation in the presence of copper catalyst. Copper-catalyzed tandem-Ullman N-alkylation and intramolecular C-H amidation reaction protocol for the synthesis of 2-phenylquinazolinone and quinazolinone derivatives from N-substituted 2-iodo-benzamides and benzylamines, allyl, and cinnamylamine is achieved.

Reaction of Schiff Bases: Part I - Convenient Synthesis of 3-Substituted 2-Styryl-4-(3H)-quinazolinones

Deodhar, K. D.,Samant, S. D.,Pednekar, S. R.,Kanekar, D. S.,Inamdar, A. A.,Patkar, P. Y.

, p. 67 - 68 (2007/10/02)

Condensation of different schiff bases (II) with 2-methyl-4H-3,1-benzoxazin-4-one (I) yields 3-substituted 2-styryl-4(3H)-quinazolinones (III) in good yields.A plausible mechanism for the reaction has been suggested.

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