2004-80-0

Basic information

• Product Name: 2-styryl-3-(o-tolyl)quinazolin-4(3H)-one
• Synonyms: 2-styryl-3-(o-tolyl)quinazolin-4(3H)-one
• CAS NO: 2004-80-0
• Molecular Weight: 338.409
• Mol File: 2004-80-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-styryl-3-(o-tolyl)quinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-styryl-3-(o-tolyl)quinazolin-4(3H)-one(2004-80-0)
• EPA Substance Registry System: 2-styryl-3-(o-tolyl)quinazolin-4(3H)-one(2004-80-0)

Safety Data

• Hazardous Substances Data: 2004-80-0(Hazardous Substances Data)

Upstream product

• 4360-51-4 cinnamylamine 
• 62303-06-4 N-(2-methylphenyl)-o-iodobenzamide 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 5877-55-4 N-benzylidene-2-methylaniline 

Relevant articles and documents

Synthesis of 2,3-Disubstituted Quinazolinone Derivatives through Copper Catalyzed C-H Amidation Reactions

The synthesis of quinazolinone derivatives was achieved from 2-iodobenzamide derivatives and various benzylamines, allylamine, and cinnamylamine derivatives through a one-pot copper-catalyzed reaction. In this reaction, the amine component (benzylamine/allylamine/cinnamylamine) is N-arylated with 2-iodobenzamide derivatives through Ullman coupling, followed by an intramolecular C-H amidation in the presence of copper catalyst. Copper-catalyzed tandem-Ullman N-alkylation and intramolecular C-H amidation reaction protocol for the synthesis of 2-phenylquinazolinone and quinazolinone derivatives from N-substituted 2-iodo-benzamides and benzylamines, allyl, and cinnamylamine is achieved.

A facile synthesis of 2,3-disubstituted 4-oxo-3,4-dihydroquinazolines

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