20043-68-9Relevant academic research and scientific papers
Spectroscopic study of 3-aryl-7-methoxy-coumarin, iminocoumarin and bis-iminocoumarin derivatives in solution
Khemakhem, Kacem,Ammar, Houcine,Abid, Souhir,El Gharbi, Rachid,Fery-Forgues, Suzanne
, p. 594 - 598 (2013)
3-Phenyl-5,7-dimethoxycoumarin and 3-(2-thienyl)-7-methoxycoumarin were strongly fluorescent in organic solution, with quantum yields reaching 0.84. In contrast, the iminocoumarin analogs of these dyes were poorly emissive. This shows that the behaviour o
New approach for the construction of the coumarin frame and application in the total synthesis of natural products
Jerezano, Alberto,Jimenez, Fabiola,Del Carmen Cruz, Maria,Montiel, Luisa E.,Delgado, Francisco,Tamariz, Joaquin
experimental part, p. 185 - 198 (2011/04/17)
A new synthetic approach is described for building the coumarin scaffold through the Lewis acid-promoted cyclization of novel aryl 3-(dimethylamino)prop- 2-enoates 2a - 2f. The latter precursors were prepared via aminomethylenation of the corresponding aryl acetates 4a - 4f with the Bredereck reagent. This approach was used for the synthesis of biologically active natural compounds 1a - 1f, through a three-step procedure starting from the corresponding phenols.
A convenient synthesis of 3-arylcoumarins from arylacetonitriles
Mhiri,Ladhar,El Gharbi,Le Bigot
, p. 1451 - 1461 (2007/10/03)
The condensation of salicylaldehydes with various arylacetonitriles catalyzed by anion-exchange resins such as Amberlite IRA 900, leads to the corresponding 3-arylcoumarins in good yields and selectivity.
A novel one-step synthesis of 3-phenyl-, 4-methyl-3-phenyl- And3-phenyl-4-styrylcoumarins using DCC-DMSO
Hans, Naresh,Singhi, Manasi,Sharma, Vibha,Grover
, p. 1159 - 1162 (2007/10/03)
2-Hydroxybenzaldehydes 1 react with phenylacetic acid and its methoxy derivatives 2 in the presence of DCC in DMSO to afford 3-phenylcoumarins 3. Under identical conditions, 2-hydroxy-acetophenones 4 and 2'-hydroxychalcones 7 give rise to the corresponding 4-methyl-3-phenyl- and 3-phenyl-4-styrylcoumarins 6 and 8, respectively.
