200556-13-4Relevant academic research and scientific papers
Synthetic studies on pentacyclic aromatic alkaloids, kuanoniamine A, 11-hydroxyascididemin, and neocalliactine acetate
Kitahara, Yoshiyasu,Nakahara, Shinsuke,Yonezawa, Takanobu,Nagatsu, Masanori,Shibano, Yoshikazu,Kubo, Akinori
, p. 17029 - 17038 (2007/10/03)
A pentacyclic aromatic alkaloid, kuanoniamine A (6) was synthesized in three steps from 6-methoxybenzothiazole-4,7-dione (8) and 2-aminoacetophenone (9). 11-Hydroxyascididemin (4) was prepared from 5,8-quinolinedione (13, 14) or 1,4-acridinedione (20). The structure of neocalliactine acetate, a derivative of calliactine, was determined to be 5 by total synthesis from 6-methoxy-5,8-quinolinedione (28) and 2-amino-5-methoxyacetophenone (29).
