200557-69-3

Upstream product

• 2633-67-2 4-vinylbenzenesulfonyl chloride 
• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 
• 2695-37-6 sodium 4-styrenesulfonate 

Relevant academic research and scientific papers

Superhydrophobic, chiral, and mesoporous TsDPEN copolymer coordinated to ruthenium species as an efficient catalyst for asymmetric transfer hydrogenation

Homogeneous chiral catalysts usually show higher catalytic activities than corresponding heterogeneous chiral catalysts, because of their easy interaction between catalytically active sites with reactant molecules. We demonstrate here superhydrophobic, chiral, and mesoporous catalysts (TsDPEN-Ru) synthesized from copolymerization of N-p-styrenesulfonyl-1,2-diphenylethylenediamine (V-TsDPEN) with divinylbenzene and loading of Ru species exhibiting much higher activities in asymmetric transfer hydrogenation (ATH) of ketones in aqueous solution than corresponding homogeneous chiral catalyst. This phenomenon is strongly related to the unique features of high enrichment for the reactants in superhydrophobic TsDPEN-Ru catalysts due to their good wettability, as well as easy transfer of product from the catalyst into water phase. These features open a door for design and developing a wide variety of chiral catalysts for asymmetric catalysis.

A pH-Responsive Soluble-Polymer-Based Homogeneous Ruthenium Catalyst for Highly Efficient Asymmetric Transfer Hydrogenation (ATH)

A pH-responsive polymer has been synthesized successfully by means of copolymerization of dimethyl aminopropyl acrylamide (DMAPA) and N-p-styrenesulfonyl-1,2-diphenylethylenediamine (V-TsDPEN). The pH-responsive polymer coordination ruthenium complex was thus prepared and employed as an efficient catalyst for the asymmetric transfer hydrogenation (ATH) of various ketones. The polymer catalyst exhibited an attractive pH-induced phase-separable behavior in water: it could be dissolved in water when the pH of the solution was lower than 6.5 at the beginning of the reaction, but was precipitated completely from water when the pH of the solution was above 8.5 after reaction. Additionally, the catalysts were highly efficient for the ATH of a wide range of substrates that bore different functional groups and could be recycled easily from the aqueous solution by means of self-separation. They could be recycled eight times without significant changes in catalytic activity and enantioselectivity.

Preparation of microgel-supported chiral catalysts and their application in the asymmetric hydrogenation of aromatic ketones

An enantiomerically pure chiral monomer (S,S)-2 was prepared and copolymerized with styrene and four different cross-linkers to produce four distinct microgel-supported chiral TsDPEN derivatives. These chiral copolymers were allowed to form complexes with

Heterogeneous Enantioselective Catalytic Reduction of Ketones

(1S,2S)-N-(styrene-p-sulfonyl)-1,2-diphenylethylenediamine was copolymerized with styrene and divinylbenzene to give functionalized polymers.These polymers were shown to be good ligands in the iridium and ruthenium catalyzed hydride transfer reduction (HT