200576-23-4Relevant academic research and scientific papers
A New Route to Substituted Dihydropyrans
Edwards,Sinclair,Wasiowych
, p. 1285 - 1286 (1997)
Deprotonation and subsequent alkylation of 3,4-dihydro-6-(para-toluenesulfonylmethyl)-2H-pyran gives monoalkylated products in good yields, with excellent α selectivity. The alkylation succeeds not only for reactive haloalkanes, but also for simple primar
Sequential cyclosulfonylation and alkylation as a versatile strategy for dihydropyran synthesis
Edwards, Gavin L.,Sinclair, David J.
, p. 3613 - 3619 (2007/10/03)
Deprotonation of 3,4-dihydro-6-(p-toluenesulfonylmethyl)-2H-pyran (2) with n-BuLi and alkylation of the lithiated allyl sulfone gives good to excellent yields of monoalkylated products 3. No γ-substitution is observed in the monoalkylated products. A seco
