200630-98-4Relevant academic research and scientific papers
C-C bond formation via C-H bond activation under protic conditions: On the role of phosphane ligand and cosolvent
Simon, Marc-Olivier,Martinez, Remi,Genet, Jean-Pierre,Darses, Sylvain
supporting information; experimental part, p. 208 - 210 (2010/04/24)
(Chemical Equation Presented) Effective conditions for the hydroarylation of vinylsilanes, allowing functionalization of various aromatic ketones in good yields at low temperature, using isopropanol, a protic solvent, are reported. Moreover, conducting th
C-C bond formation via C-H bond activation using an in situ-generated ruthenium catalyst
Martinez, Remi,Simon, Marc-Olivier,Chevalier, Reynald,Pautigny, Cyrielle,Genet, Jean-Pierre,Darses, Sylvain
supporting information; experimental part, p. 7887 - 7895 (2009/10/17)
We report here our full results concerning the possibility of generatingin situ from a stable and readily available ruthenium(II) source a high ly active ruthenium catalyst for C-H bond activation. The versatility ofthis catalytic system has been demonstrated, as it offers the possibili ty of modifying the electronic and steric properties of the catalyst by fine-tuning of the ligands, allowing functionalization of various substrates. Aromatic ketones and imines could be easily functionalized by the reaction with either vinylsilanes or styrenes, depending on the electronic and steric nature of the ligand. Moreover, variable-temperature NMR experiments and the isolation of a ruthenium intermediate complex provided some insights into the generation of the active catalytic ruthenium species in this reaction.
Ruthenium-Catalyzed Addition of Carbon-Hydrogen Bonds in Aromatic Ketones to Olefins. The Effect of Various Substituents at the Aromatic Ring
Sonoda, Motohiro,Kakiuchi, Fumitoshi,Chatani, Naoto,Murai, Shinji
, p. 3117 - 3128 (2007/10/03)
To obtain further insight into the new ruthenium-catalyzed reaction of carbon-hydrogen bonds in aromatic ketones with olefins, the effect of various substituents at the aromatic ring is examined. Reaction of o-methylacetophenone with triethoxyvinylsilane
Directing effect of functional groups in ruthenium-catalyzed addition of substituted acetophenones to an olefin
Sonoda, Motohiro,Kakiuchi, Fumitoshi,Chatani, Naoto,Murai, Shinji
, p. 151 - 152 (2007/10/03)
Ruthenium-catalyzed addition of 3'-methyl-, 3'-trifluoromethyl-, and 3'-N,N-dimethylaminoacetophenones to an olefin proceeds site selectively at 6' C-H bonds to give the 1:1 C-H/olefin addition products in high yields.In contrast, the addition of 3'-metho
