20073-80-7

Basic information

• Product Name: Benzene-1,4-dicarbohydroxamic acid
• Synonyms: 1,4-Benzenedicarbohydroximic acid;Benzene-1,4-dicarbohydroxamic acid;N,N'-(p-Phenylenebiscarbonyl)dihydroxylamine;N,N'-Dihydroxy-1,4-benzenedicarboxamide;Terephthalohydroxamic acid;WR-74106
• CAS NO: 20073-80-7
• Molecular Formula: C₈H₈N₂O₄
• Molecular Weight: 196.1601
• Mol File: 20073-80-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 236 °C (decomp)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.484g/cm³
• PKA: 8.20±0.10(Predicted)
• CAS DataBase Reference: Benzene-1,4-dicarbohydroxamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene-1,4-dicarbohydroxamic acid(20073-80-7)
• EPA Substance Registry System: Benzene-1,4-dicarbohydroxamic acid(20073-80-7)

Safety Data

• Hazardous Substances Data: 20073-80-7(Hazardous Substances Data)

Upstream product

• 100-20-9 terephthaloyl chloride 
• 1426580-49-5 N,N'-bis-(2,3-dimethyl-but-2-enyloxy)terephthalamide 
• 120-61-6 1,4-benzenedicarboxylic acid dimethyl ester 

Downstream Products

• 106-50-3 1,4-phenylenediamine 
• 15568-81-7 5,5,5',5'-tetramethyl-3,3'-p-phenylene-bis-[1,4,2]dioxazole 
• 30240-10-9 Diacetylterephthalohydroxamat 
• 22159-13-3 3,3′-(1,4-phenylene)bis(1,4,2-dioxazol-5-one) 
• 64125-08-2 5,5'-bis-methoxycarbonylmethyl-3,3'-p-phenylene-bis-[1,4,2]dioxazole-5-carboxylic acid dimethyl ester 

Relevant articles and documents

Synthetic Modularity of Protein-Metal-Organic Frameworks

Previously, we adopted the construction principles of metal-organic frameworks (MOFs) to design a 3D crystalline protein lattice in which pseudospherical ferritin nodes decorated on their C3 symmetric vertices with Zn coordination sites were connected via a ditopic benzene-dihydroxamate linker. In this work, we have systematically varied both the metal ions presented at the vertices of the ferritin nodes (Zn(II), Ni(II), and Co(II)) and the synthetic dihydroxamate linkers, which yielded an expanded library of 15 ferritin-MOFs with the expected body-centered (cubic or tetragonal) lattice arrangements. Crystallographic and small-angle X-ray scattering (SAXS) analyses indicate that lattice symmetries and dimensions of ferritin-MOFs can be dictated by both the metal and linker components. SAXS measurements on bulk crystalline samples reveal that some ferritin-MOFs can adopt multiple lattice conformations, suggesting dynamic behavior. This work establishes that the self-assembly of ferritin-MOFs is highly robust and that the synthetic modularity that underlies the structural diversity of conventional MOFs can also be applied to the self-assembly of protein-based crystalline materials.

Tunable and Cooperative Thermomechanical Properties of Protein-Metal-Organic Frameworks

We recently introduced protein-metal-organic frameworks (protein-MOFs) as chemically designed protein crystals, composed of ferritin nodes that predictably assemble into 3D lattices upon coordination of various metal ions and ditopic, hydroxamate-based li

New emissive organic molecule based on pyrido[3,4-g]isoquinoline framework: Synthesis and fluorescence tuning as well as optical waveguide behavior

In this paper we report the synthesis and crystal structures of emissive organic molecule (1a) based on pyrido[3,4-g]isoquinoline framework as well as its isomers 1b and 1c. The emission quantum yields decrease after transformation of pyridine moieties in 1a into the cyclic-amides in 1b and 1c. The fluorescent spectral results reveal that 1a, 1b, and 1c exhibit no AIE behavior. This is tentatively attributed to intramolecular weak C?H interactions, which may impede the intramolecular rotations based on the crystal structures of 1a and 1c. Interestingly, 1a, 1b, and 1c are emissive in the solid state, and among them 1a possesses the highest emission quantum yield (0.22). Moreover, the fluorescence of 1a in solution and solid state can be reversibly tuned by reactions with trifluoroacetic acid and triethylamine. Microarea PL studies reveal that microrods of 1a and these after exposure to HCl gas show typical waveguide behavior.